It would surely bring up a lot of attention to  CML and it's victims. Most
people don't realize much about it.

18's,

Marty

On Sat, Nov 15, 2014 at 10:41 AM, Myvety2k via CMLHope <
cmlhope@googlegroups.com> wrote:

>  Marty,  that's not a bad idea, he should contact them.
>
> greenie
>
>  In a message dated 11/15/2014 10:31:59 A.M. Eastern Standard Time,
> wa2...@gmail.com writes:
>
>  Hey Skip, you say "been on all the different chemos just like school I
> failed every one"
>
> Well, you may have been on all of them but you didn't fail. And do you
> want to know why? Hey your still here after all of these years. [?]
>
> I think that sending you those 18's really speaks volumes.
>
> Skip you need to make awareness of CML as probably the longest person in
> the world alive with CML. Ever think about contacting the Guiness world
> book of records?
>
> 18's,
>
> Marty
>
> On Sat, Nov 15, 2014 at 8:46 AM, Myvety2k via CMLHope <
> cmlhope@googlegroups.com> wrote:
>
>>  Marty, very well spoken.
>>
>> greenie
>>
>>  In a message dated 11/15/2014 8:43:02 A.M. Eastern Standard Time,
>> wa2...@gmail.com writes:
>>
>> Hi Greenie,
>>
>> This ship that we are all in command of is a very special ship. Do you
>> want to know why? Well, it is always afloat and never sinks. Even if you
>> have some bad days, and I can certainly attest to that, then we also have
>> those good days. So we seem to be sailing in the right direction.
>>
>> My father once taught me that every day is a good day as long as none of
>> our loved ones dies. I was in that plastic bubble when he came and sat
>> right in front of it. I was kind of feeling really bad until he told me
>> that. GOD rest his soul...
>>
>> 18's,
>>
>> Marty
>>
>> On Sat, Nov 15, 2014 at 7:20 AM, Myvety2k via CMLHope <
>> cmlhope@googlegroups.com> wrote:
>>
>>>  Well thank you Marcie,  I have this idea, let's make Skip a Fleet
>>> Admiral, I'm not sure but I think he as had CML the longest. Will make
>>> Marty Admiral that's next in line and I'll be Captain Dave.  When I first
>>> started flying real planes my instructor used to call me Capt. Dave.  So
>>> when I started flying RC airplanes last year I crashed a lot so one of the
>>> guy's would call me Danger Dave.  Of course now I can fly as good as the
>>> rest of the guys.  But their used to be a lot of broken plane parts on the
>>> field.
>>>
>>> greenie
>>>
>>>
>>>  In a message dated 11/14/2014 10:51:23 P.M. Eastern Standard Time,
>>> cmlhope@googlegroups.com writes:
>>>
>>> Greenie, we are all so thrilled you are doing well. If Marty is our
>>> captain, I think you must be his first officer!
>>>
>>> Marcie
>>>
>>> Sent from my iPad
>>>
>>> On Nov 14, 2014, at 9:38 PM, Myvety2k via CMLHope <
>>> cmlhope@googlegroups.com> wrote:
>>>
>>>  I would like to thank each and everyone of you for your warm hearted
>>> replies.
>>>
>>> greenie
>>>
>>>  In a message dated 11/14/2014 9:36:20 P.M. Eastern Standard Time,
>>> cmlhope@googlegroups.com writes:
>>>
>>> Thank you Marty,  I should have added that I went into remission within
>>> 6 months after starting Gleevec.  I was having to get blood work every 3
>>> months now I get blood work every 6 months.  I've had 27 BMB's so I'm glad
>>> they do it by testing your blood. We all have our good days and then their
>>> are a few bad days to so like my late Aunt used to say just take one day at
>>> a time.  And that's what I do.  Today was one of those bad days but
>>> tomorrow I'm sure will be better it always is. Everyone please take care of
>>> yourself's I'm so lucky my wife Grace who takes good care of me.
>>>
>>> greenie
>>>
>>>
>>>  In a message dated 11/14/2014 7:35:36 P.M. Eastern Standard Time,
>>> wa2...@gmail.com writes:
>>>
>>> Greenie,
>>>
>>> Hey, what took you so long? I am thrilled to hear this wonderful news.
>>> You are blessed.
>>>
>>> 18's,
>>>
>>> Marty
>>>
>>> On Fri, Nov 14, 2014 at 2:29 PM, icandoallttc via CMLHope <
>>> cmlhope@googlegroups.com> wrote:
>>>
>>>>  Yahoo Greenie
>>>> So happy for you!!
>>>> Blessing
>>>> Jeanie
>>>>
>>>> Sent from my iPhone
>>>>
>>>> On Nov 11, 2014, at 4:05 PM, Myvety2k via CMLHope <
>>>> cmlhope@googlegroups.com> wrote:
>>>>
>>>>  I received my results back from my 6 month blood work today and I'm
>>>> Negative on BCR-ABL.
>>>>
>>>> greenie
>>>>
>>>>  In a message dated 11/11/2014 2:14:49 P.M. Eastern Standard Time,
>>>> cmlhope@googlegroups.com writes:
>>>>
>>>> Happy Veterans Day to all
>>>> JeanieđŸŒČđŸ‡ș🇾đŸ‡ș🇾
>>>>
>>>> Sent from my iPhone
>>>>
>>>> On Nov 11, 2014, at 1:56 PM, Myvety2k via CMLHope <
>>>> cmlhope@googlegroups.com> wrote:
>>>>
>>>>  Thank you Elizabeth,  I served 6 years in the Navy.
>>>>
>>>> greenie
>>>>
>>>>  In a message dated 11/11/2014 1:43:34 P.M. Eastern Standard Time,
>>>> ksnwo...@prodigy.net writes:
>>>>
>>>>  Thinking of you all.  Nick is critically anemic due to Gleevec.  Hope
>>>> Richard H., Shannon, Bobbie Doyle, and all keep  up your sharing of info.
>>>> thanks so much Marty for the reports from the clinical trials to reduce or
>>>> stop Gleevec.
>>>> Thank you to all Veterans on this day.  Elizabeth Woods
>>>>
>>>>
>>>>   On Tuesday, November 11, 2014 4:32 AM, "cmlhope@googlegroups.com" <
>>>> cmlhope@googlegroups.com> wrote:
>>>>
>>>>
>>>>     cmlhope@googlegroups.com
>>>> <https://groups.google.com/forum/?utm_source=digest&utm_medium=email/#!forum/cmlhope/topics>
>>>>  Google
>>>> Groups
>>>> <https://groups.google.com/forum/?utm_source=digest&utm_medium=email/#!overview>
>>>>  [image:
>>>> https://groups.google.com/forum/?utm_source=digest&utm_medium=email/#!overview]
>>>> <https://groups.google.com/forum/?utm_source=digest&utm_medium=email/#!overview>
>>>>  Topic digest
>>>> View all topics
>>>> <https://groups.google.com/forum/?utm_source=digest&utm_medium=email/#!forum/cmlhope/topics>
>>>>
>>>>    - Glivec and studies of stopping the drug
>>>>    
>>>> <https://us-mg205.mail.yahoo.com/neo/launch?.partner=sbc&.rand=8fv0d9j9nknkk#group_thread_0>
>>>>    - 1 Update
>>>>    - Digest for cmlhope@googlegroups.com - 6 updates in 2 topics
>>>>    
>>>> <https://us-mg205.mail.yahoo.com/neo/launch?.partner=sbc&.rand=8fv0d9j9nknkk#group_thread_1>
>>>>    - 1 Update
>>>>
>>>> Glivec and studies of stopping the drug
>>>> <http://groups.google.com/group/cmlhope/t/839da881a2e6e455?utm_source=digest&utm_medium=email>
>>>>  Richard H <rbhuffm...@gmail.com>: Nov 10 09:05PM -0800
>>>>
>>>> Yes. This was the reason I stopped Gleevec. I was also had Iron
>>>> Deficient
>>>> Anemia. I had to infuse the iron to help try to recover my RBC count
>>>> because was below 9. I was also still taking Gleevec while doing this.
>>>> On Monday, November 10, 2014 12:56:18 AM UTC-6, Shannon L wrote:
>>>> Back to top
>>>> <https://us-mg205.mail.yahoo.com/neo/launch?.partner=sbc&.rand=8fv0d9j9nknkk#digest_top>
>>>> Digest for cmlhope@googlegroups.com - 6 updates in 2 topics
>>>> <http://groups.google.com/group/cmlhope/t/6cf9af24d4b963a7?utm_source=digest&utm_medium=email>
>>>>  "Sue" <hol...@iinet.net.au>: Nov 10 07:13PM +0800
>>>>
>>>> Hi Shannon
>>>>
>>>>
>>>>
>>>> There is also the Destiny Trial in the UK which is reduction down to
>>>> 200mg for 12 months and then stop (there has been no report until after Dec
>>>> 2014)
>>>>
>>>> The next Trial is named Spirit3 to see if people are being over
>>>> medicated
>>>>
>>>>
>>>>
>>>> The Australian Survey will have 600 participants
>>>>
>>>>
>>>>
>>>> Sue Hurt
>>>>
>>>> (Australian)
>>>>
>>>>
>>>>
>>>> From: cmlhope@googlegroups.com [mailto:cmlhope@googlegroups.com
>>>> <cmlhope@googlegroups.com>]
>>>> Sent: Monday, 10 November 2014 6:22 PM
>>>> To: Digest recipients
>>>> Subject: [CMLHope] Digest for cmlhope@googlegroups.com - 6 updates in
>>>> 2 topics
>>>>
>>>>
>>>>
>>>>
>>>> cmlhope@googlegroups.com
>>>>
>>>> <
>>>> https://groups.google.com/forum/?utm_source=digest&utm_medium=email/#!overview>
>>>> Google Groups
>>>>
>>>> <
>>>> https://groups.google.com/forum/?utm_source=digest&utm_medium=email/#!overview>
>>>>
>>>>
>>>> Topic digest
>>>> View all topics
>>>>
>>>> * Glivec and studies of stopping the drug - 5 Updates
>>>>
>>>> * Glivec and studies of stopping the drug - 1 Update
>>>>
>>>> <
>>>> http://groups.google.com/group/cmlhope/t/839da881a2e6e455?utm_source=digest&utm_medium=email>
>>>> Glivec and studies of stopping the drug
>>>>
>>>>
>>>> Shannon L <shannonl.cam...@gmail.com <mailto:shannonl.cam...@gmail.com
>>>> <shannonl.cam...@gmail.com>> >: Nov 09 03:58AM -0800
>>>>
>>>> Hi All My name is Shannon I live in Sydney Australia
>>>> Its been awhile since I have posted.
>>>> I was diagnosed 1998 and after a few years went onto sti571 (glivec)
>>>> and
>>>> achieved remission within 2 months and I have been it ever since about
>>>> 14
>>>> yrs.
>>>> They are inviting participants (in Australia) to take a survey of
>>>> stopping
>>>> glivec I image they will do a study of stopping the drug.
>>>> My question is does everyone know of the study done in USA of the stats
>>>> of
>>>> stopping they have indicated in this survey info that the percentage of
>>>> success is 30-40% to me that SEEMS LOW what do you think.
>>>> I do have some problems but I am stable on glivec.
>>>> I hope this emil finds everyone well
>>>> Shannon
>>>>
>>>>
>>>> Marty Gartenberg <wa2...@gmail.com <mailto:wa2...@gmail.com
>>>> <wa2...@gmail.com>> >: Nov 09 07:46AM -0500
>>>>
>>>> Hi Shannon, there is a study called the STIM that is going on in the UK
>>>> and
>>>> it talks about Imatinib being stopped. It is kind of lengthily however
>>>> it
>>>> does go into detail.
>>>> Good luck to you, and I have always said there will be a cure for CML in
>>>> our lifetimes.
>>>> If you follow any of my posts I always end them with two numbers. They
>>>> are
>>>> 18 which is the symbol for life.
>>>> 18's to you Shannon
>>>> Marty
>>>> PS Shannon I encourage you to post any time that you like. There will
>>>> usually be someone that may be able to answer your questions. Besides
>>>> that
>>>> we are all here to learn from and help each other
>>>> Can Imatinib Be Stopped?
>>>>
>>>> Goodwin, Peter
>>>> Article Outline
>>>> [image: Collapse Box]Author Information
>>>>
>>>> ASH Abstracts 186 and 187
>>>>
>>>> SAN FRANCISCO—The early promise of the tyrosine kinase inhibitor (TKI)
>>>> imatinib for treating chronic myeloid leukemia (CML) has continued to be
>>>> fulfilled following the release of seven-year follow-up data at the ASH
>>>> Annual Meeting here from the International Randomized Study of
>>>> Interferon
>>>> versus STI 571 (imatinib) (IRIS) with 553 patients.
>>>>
>>>> With diminishing rates of progression each year beyond year three, the
>>>> case
>>>> for stopping imatinib altogether was also discussed at the meeting
>>>> following release of results from two studies in which the drug was
>>>> discontinued among patients who had achieved enduring complete molecular
>>>> responses to it for more than two years.
>>>>
>>>> IRIS investigator Stephen G. O'Brien MD, PhD, Senior Lecturer in
>>>> Experimental Hematology at Northern Institute for Cancer Research of
>>>> University of Newcastle upon Tyne, UK, gave the latest IRIS results to a
>>>> packed audience at the meeting, showing an event-free survival rate of
>>>> 81%,
>>>> freedom from progression to accelerated phase/blast crisis of 93%, and
>>>> an
>>>> estimated overall survival rate of 86%, from the standard dose of 400 mg
>>>> imatinib daily.
>>>>
>>>> And in the presentation that followed, François-Xavier Mahon, MD,
>>>> Professor
>>>> at Victor SĂ©galen University in Bordeaux, France, released early data
>>>> from
>>>> the Stop Imatinib (STIM) study, noting that remissions continued in
>>>> about
>>>> half of the patients after investigational discontinuation of imatinib
>>>> therapy—with a non-significant trend showing that patients previously
>>>> treated with interferon were more likely to be among those whose
>>>> remissions
>>>> persisted without drugs.
>>>>
>>>> Dr. O'Brien said that in IRIS the projected cytogenetic response rate to
>>>> imatinib (by Kaplan Meyer analysis) was 82%, and that after seven years
>>>> of
>>>> follow-up 60% of patients were still on imatinib, with 57% of all
>>>> patients
>>>> still in complete cytogenetic response (CCR).
>>>>
>>>> The impression that CCR holds the key to a “cure” of CML was
>>>> strengthened
>>>> by comments he made after his talk:
>>>>
>>>> “It seems that if you maintain your CCR for, say, three years, the
>>>> chance
>>>> of regressing at that point is essentially zero. So, achieving a CCR
>>>> is, I
>>>> guess, what we call a ‘safe haven’ for the majority of patients: If
>>>> you've
>>>> achieved that and sustained it for, say, three years, you're in pretty
>>>> good
>>>> shape and the chance of progressing is virtually nil,” he said.
>>>> Back to Top
>>>> <
>>>> http://journals.lww.com/oncology-times/Fulltext/2009/02101/Can_Imatinib_Be_Stopped_.1.aspx#
>>>> <
>>>> http://journals.lww.com/oncology-times/Fulltext/2009/02101/Can_Imatinib_Be_Stopped_.1.aspx>
>>>> >
>>>> | Article Outline
>>>> Diminishing Rates of Relapse
>>>>
>>>> These words reflect the diminishing rates of relapse observed in the
>>>> IRIS
>>>> study in successive years. Rates of progression to accelerate phase or
>>>> blast crisis each year were low at all times—with rates rising in the
>>>> first
>>>> two years (1.5% in the first year; 2.8% in the second year) and then
>>>> diminishing after that (1.6%, 0.9%, 0.5%, 0%, 0.4% in years 3, 4, 5, 6,
>>>> and
>>>> 7, respectively)—with only a single patient having disease progression
>>>> to
>>>> accelerate phase or blast crisis between years six and seven.
>>>> [image: Figure. FRANOIS-XAVI...]
>>>> Figure. FRANOIS-XAVI...
>>>> Image Tools
>>>>
>>>> The total annual event rates, including loss of molecular complete
>>>> remission and death, were similarly low (3.3% and 7.5%) in years one and
>>>> two, and diminished thereafter (4.8%, 1.7%, 0.8%, 0.3%, and 2.0% in
>>>> years
>>>> three through seven).
>>>>
>>>> These data only apply, of course, to the majority of patients who prove
>>>> sensitive to imatinib, and Dr. O'Brien noted that many patients who are
>>>> resistant or refractory to the TKI are now candidates for other drugs
>>>> and
>>>> in some cases, allogeneic transplantation.
>>>>
>>>> Dr. O'Brien summed up his feelings about the current state of the art
>>>> concerning imatinib therapy for CML: “I think it's encouraging on two
>>>> fronts. One is that there's nothing new in years six and seven to cause
>>>> alarm in terms of safety events. And the second is—particularly in
>>>> patients
>>>> who achieved a complete cytogenetic response—I think we can be very
>>>> reassured that the vast majority—especially if you have that CCR for
>>>> three
>>>> years—are doing extremely well, with very few of those progressing.”
>>>> Back to Top
>>>> <
>>>> http://journals.lww.com/oncology-times/Fulltext/2009/02101/Can_Imatinib_Be_Stopped_.1.aspx#
>>>> <
>>>> http://journals.lww.com/oncology-times/Fulltext/2009/02101/Can_Imatinib_Be_Stopped_.1.aspx>
>>>> >
>>>> | Article Outline
>>>> STIM Study
>>>>
>>>> Encouraging data on long-term remission of CML among patients treated
>>>> with
>>>> imatinib gave rise to the French initiative to conduct a pilot study
>>>> with
>>>> 15 patients looking at stopping imatinib, and following this the
>>>> multicenter STIM study with 50 patients, which began in July 2007 but
>>>> which
>>>> has already yielded early—but provocative—evidence that remission from
>>>> CML
>>>> can continue even after imatinib is stopped.
>>>>
>>>> Dr. Mahon said that patients were recruited into these studies only if
>>>> they
>>>> had received imatinib for at least three years and achieved sustained
>>>> complete molecular remission (CMR) for two years before experimentally
>>>> stopping the drug.
>>>>
>>>> The definition of sustained CMR was strict: BCR-ABL/ABL had to be below
>>>> a
>>>> detection threshold corresponding to a 5-log reduction (undetectable
>>>> signal
>>>> using RQ-PCR) for at least two years. Molecular relapse was defined as
>>>> RQ-PCR positivity detected in two successive assays, and patients who
>>>> relapsed were then retreated with imatinib (successfully) at a dose of
>>>> 400
>>>> mg daily.
>>>>
>>>> In the latest follow-up of the pilot study, Dr. Mahon said that seven
>>>> out
>>>> of 15 patients had relapse within six months and all were restored to
>>>> CMR
>>>> by re-treatment with imatinib. The remaining eight patients were still
>>>> in
>>>> CMR a median of 37 months after stopping the drug.
>>>>
>>>> All of the patients in the pilot study had been treated with interferon
>>>> before receiving imatinib, most of them responding to it. This raised
>>>> the
>>>> suggestion—which Dr. Mahon discussed in his talk at the ASH meeting—that
>>>> interferon may have conferred a benefit among patients who were
>>>> subsequently treated with imatinib.
>>>>
>>>> Half of the patients in the STIM study had been pretreated with
>>>> interferon,
>>>> and some provocative—but as yet not statistically significant—data have
>>>> emerged showing an advantage among those who had previously received
>>>> interferon before going on to imatinib therapy.
>>>>
>>>> By July 2008, 10 of the 15 patients who were still in CMR had received
>>>> prior interferon. The latest assessment from a slide Dr. Mahon presented
>>>> showed that 27 out of 49 patients followed for more than six months had
>>>> had
>>>> disease relapse; 14 of these had received only imatinib and the
>>>> remaining
>>>> 13 had been previously treated with interferon, while only two of the
>>>> seven
>>>> patients in STIM who have so far continued in CMR for 14 months had been
>>>> treated with imatinib alone.
>>>>
>>>> Dr. Mahon summed up his interim conclusions by stating that they have
>>>> confirmed that CMR can be sustained after stopping imatinib, and that
>>>> although there seems to be an [as yet statistically unconfirmed]
>>>> advantage
>>>> among the patients who received interferon, it is possible to stop the
>>>> drug
>>>> in patients with sustained CMR even among those treated with imatinib
>>>> alone.
>>>>
>>>> He reported that the probability of survival without molecular relapse
>>>> nine
>>>> months after discontinuing imatinib was 46%, with the curve looking
>>>> flat,
>>>> so far, out to 15 months. Importantly, the STIM study found that all
>>>> patients were sensitive after imatinib re-challenge.
>>>> Back to Top
>>>> <
>>>> http://journals.lww.com/oncology-times/Fulltext/2009/02101/Can_Imatinib_Be_Stopped_.1.aspx#
>>>> <
>>>> http://journals.lww.com/oncology-times/Fulltext/2009/02101/Can_Imatinib_Be_Stopped_.1.aspx>
>>>> >
>>>> | Article Outline
>>>> ‘Recurring Question’
>>>>
>>>> When Dr. O'Brien was asked for a comment on Dr. Mahon's conclusion from
>>>> the
>>>> initial pilot study and the early results from the STIM study, he said,
>>>> “I'm fascinated by it. There's probably a bit of a cultural difference,
>>>> I
>>>> think, because most of my patients in the UK—when I suggest
>>>> [stopping]—don't want to hand their pills back, and want to carry on.
>>>> [image: Figure. STEPHEN G. O...]
>>>> Figure. STEPHEN G. O...
>>>> Image Tools
>>>>
>>>> “I think that's driven by the fact that they are tolerating the drug
>>>> well.
>>>> There are no safety concerns emerging with the long-term follow-up. And
>>>> it's obviously having good efficacy in them. But this is a recurring
>>>> question that I think we'll see more and more of—and the French study is
>>>> very important.”
>>>> Back to Top
>>>> <
>>>> http://journals.lww.com/oncology-times/Fulltext/2009/02101/Can_Imatinib_Be_Stopped_.1.aspx#
>>>> <
>>>> http://journals.lww.com/oncology-times/Fulltext/2009/02101/Can_Imatinib_Be_Stopped_.1.aspx>
>>>> >
>>>> | Article Outline
>>>> Low Toxicities
>>>>
>>>> In the UK, he noted, the preference for continuing imatinib could be
>>>> explained by relatively low toxicities, which were not a significant
>>>> barrier to its use, with neutropenia and thrombocytopenia being minor
>>>> toxicities that are merely irritating over time.
>>>>
>>>> “GI toxicity like diarrhea, for example, and a feeling of fatigue and
>>>> malaise, sometimes, and muscle cramps can be troublesome in some
>>>> patients
>>>> over the years. But they're usually minor toxicities which, after many
>>>> years, become rather wearing, rather than major toxicities,” he said.
>>>>
>>>> The bottom line for clinicians treating their patients with CML,
>>>> according
>>>> to Dr. O'Brien's interpretation of his IRIS results, is that imatinib at
>>>> 400 mg remains the current standard for first-line drug therapy, even
>>>> though there are exciting data among patient cohorts treated with
>>>> nilotinib
>>>> and dasatinib first-line, with cytogenetic response rates in excess of
>>>> 95%.
>>>>
>>>> “I think—for the future—where we're going is to do comparative Phase III
>>>> studies with the tyrosine kinase inhibitors in newly diagnosed patients
>>>> to
>>>> see if we can improve on imatinib. Because although the imatinib data is
>>>> reassuring, it's clear that at six or seven years, perhaps a third of
>>>> patients are not continuing on imatinib,” he said.
>>>>
>>>> *Supported by funding from Genentech BioOncology and Biogen Idec.*
>>>>
>>>> © 2009 Lippincott Williams & Wilkins, Inc.
>>>>
>>>>
>>>>
>>>> Shannon L <shannonl.cam...@gmail.com <mailto:shannonl.cam...@gmail.com
>>>> <shannonl.cam...@gmail.com>> >: Nov 09 03:52PM -0800
>>>>
>>>> Hi Everyone
>>>> Thankyou Marty for the research information it was very informative, so
>>>> they are combining stopping with interferon unfortunately I can't
>>>> tolerate
>>>> it I remember the first time before glivec.
>>>> I hope everyone is having a wonderful day.
>>>>
>>>> On Sunday, November 9, 2014 10:58:55 PM UTC+11, Shannon L wrote:
>>>>
>>>>
>>>> Richard H <rbhuffm...@gmail.com <mailto:rbhuffm...@gmail.com
>>>> <rbhuffm...@gmail.com>> >: Nov 09 09:33PM -0800
>>>>
>>>> What a great record. You didn't indicate how much Gleevec you are
>>>> taking.
>>>> I have read that several CMLers are taking reduced amounts and reaming
>>>> in
>>>> remission. I have seen a post by a lady that said see was very petite
>>>> and
>>>> she was only taking 100mg instead of 400mg.
>>>> I don't know the percentage or of a combined results From the different
>>>> studies I read sometime ago I believe the range you have is consistent
>>>> with
>>>> what I have read. You can read my results below. My ONC told be I
>>>> needed
>>>> to end my almost 6 year vacation and I am trying to requalify for a
>>>> lower
>>>> copay for Bosutinib. I have tested and they found no mutation. I have
>>>> studied the side effects and I will be meeting with a Nurse to go over
>>>> the
>>>> side effects. Due to my other problems I am concerned about all the
>>>> interactions with those Meds.
>>>> I hope this has helped you.
>>>>
>>>> Richard H.
>>>>
>>>> Dxd 2/2003
>>>>
>>>> 400mg Gleevec 3/2003
>>>>
>>>> Undetectable 11/03
>>>>
>>>> RT-PCR negative 11/04
>>>>
>>>> QT-PCR .003 11/05
>>>>
>>>> RBC 8.
>>>>
>>>> Gleevec Vacation 11/06-6/07
>>>>
>>>> Iron infusion 11/06
>>>>
>>>> Transfusions 12/06-5/07
>>>>
>>>> QT-PCR .007
>>>>
>>>> Gleevec 1/08 -5/08
>>>>
>>>> Procrit 8/08-11/08
>>>>
>>>> Gleevec Vacation 7/08-Present
>>>>
>>>> QT-PCR .003 4/09
>>>>
>>>> QT-PCR .0015 6/09
>>>>
>>>> QT-PCR .0021 9/09
>>>>
>>>> QT-PCR .0028 1/10
>>>>
>>>> QT-PCR .001 4/10
>>>>
>>>> QT-PCR .00468 10/10
>>>>
>>>> QT-PCR 1.049% 2/11
>>>>
>>>> QT-PCR .0612% 8/11
>>>>
>>>> QT-PCR 2.616 % 2/12
>>>>
>>>> QT-PCR 2.410% 8/12
>>>>
>>>> RT-PCR 9.183% 4/13
>>>>
>>>> RT-PCR 4.57% 6/13
>>>>
>>>> RT-PCR 10.183% 10/13
>>>>
>>>> RT-PCR 10.577% 2/14
>>>>
>>>> RT-PCR 16.050% 5/14
>>>>
>>>> On Sunday, November 9, 2014 5:58:55 AM UTC-6, Shannon L wrote:
>>>>
>>>>
>>>>
>>>> Shannon L <shannonl.cam...@gmail.com <mailto:shannonl.cam...@gmail.com
>>>> <shannonl.cam...@gmail.com>> >: Nov 09 10:56PM -0800
>>>>
>>>> Hi Richard H
>>>>
>>>> Yes Glivec 400 mg has been good to me I have been very stable on the
>>>> drug,
>>>> Wow 6 years off glivec thank you so much for sharing your results just
>>>> a
>>>> question in your first holiday off glivec you had an iron injection is
>>>> this
>>>> because of cml? I am contemplating a small break as my stomach problems
>>>> seem to be increasing and are at times very debilitating. I know I have
>>>> been on many meds prior to glivec (chemo twice, cytarabine, hydroxia,
>>>> and
>>>> interferon) and Im sure my body sometimes struggles with it all.
>>>>
>>>> On Sunday, November 9, 2014 10:58:55 PM UTC+11, Shannon L wrote:
>>>>
>>>> Back to top
>>>>
>>>> <
>>>> http://groups.google.com/group/cmlhope/t/22ca310a00448c54?utm_source=digest&utm_medium=email>
>>>> Glivec and studies of stopping the drug
>>>>
>>>>
>>>> myvet...@aol.com <mailto:myvet...@aol.com <myvet...@aol.com>> : Nov 09
>>>> 07:32AM -0500
>>>> Back to top
>>>> <https://us-mg205.mail.yahoo.com/neo/launch?.partner=sbc&.rand=8fv0d9j9nknkk#digest_top>
>>>>   You received this digest because you're subscribed to updates for
>>>> this group. You can change your settings on the group membership page
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>>>> .
>>>> To unsubscribe from this group and stop receiving emails from it send
>>>> an email to cmlhope+unsubscr...@googlegroups.com.
>>>>
>>>>
>>>> --
>>>> --
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>>>>
>>>> --
>>>> --
>>>> [CMLHope]
>>>> A support group of http://cmlhope.com
>>>> -------------------------------------------------
>>>>
>>>> You received this message because you are subscribed to the Google
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>>>> To post to this group, send email to CMLHope@googlegroups.com
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>>>> ---
>>>> You received this message because you are subscribed to the Google
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>>>>
>>>> --
>>>> --
>>>> [CMLHope]
>>>> A support group of http://cmlhope.com
>>>> -------------------------------------------------
>>>>
>>>> You received this message because you are subscribed to the Google
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>>>> To post to this group, send email to CMLHope@googlegroups.com
>>>> To unsubscribe from this group, send email to
>>>> cmlhope-unsubscr...@googlegroups.com
>>>> For more options, visit this group at
>>>> http://groups.google.com/group/CMLHope
>>>> ---
>>>> You received this message because you are subscribed to the Google
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>>>> an email to cmlhope+unsubscr...@googlegroups.com.
>>>> For more options, visit https://groups.google.com/d/optout.
>>>>
>>>> --
>>>> --
>>>> [CMLHope]
>>>> A support group of http://cmlhope.com
>>>> -------------------------------------------------
>>>>
>>>> You received this message because you are subscribed to the Google
>>>> Groups "CMLHope" group.
>>>> To post to this group, send email to CMLHope@googlegroups.com
>>>> To unsubscribe from this group, send email to
>>>> cmlhope-unsubscr...@googlegroups.com
>>>> For more options, visit this group at
>>>> http://groups.google.com/group/CMLHope
>>>> ---
>>>> You received this message because you are subscribed to the Google
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>>>> To unsubscribe from this group and stop receiving emails from it, send
>>>> an email to cmlhope+unsubscr...@googlegroups.com.
>>>> For more options, visit https://groups.google.com/d/optout.
>>>>
>>>> --
>>>> --
>>>> [CMLHope]
>>>> A support group of http://cmlhope.com
>>>> -------------------------------------------------
>>>>
>>>> You received this message because you are subscribed to the Google
>>>> Groups "CMLHope" group.
>>>> To post to this group, send email to CMLHope@googlegroups.com
>>>> To unsubscribe from this group, send email to
>>>> cmlhope-unsubscr...@googlegroups.com
>>>> For more options, visit this group at
>>>> http://groups.google.com/group/CMLHope
>>>> ---
>>>> You received this message because you are subscribed to the Google
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>>>> To unsubscribe from this group and stop receiving emails from it, send
>>>> an email to cmlhope+unsubscr...@googlegroups.com.
>>>> For more options, visit https://groups.google.com/d/optout.
>>>>
>>>
>>> --
>>> --
>>> [CMLHope]
>>> A support group of http://cmlhope.com
>>> -------------------------------------------------
>>>
>>> You received this message because you are subscribed to the Google
>>> Groups "CMLHope" group.
>>> To post to this group, send email to CMLHope@googlegroups.com
>>> To unsubscribe from this group, send email to
>>> cmlhope-unsubscr...@googlegroups.com
>>> For more options, visit this group at
>>> http://groups.google.com/group/CMLHope
>>> ---
>>> You received this message because you are subscribed to the Google
>>> Groups "CMLHope" group.
>>> To unsubscribe from this group and stop receiving emails from it, send
>>> an email to cmlhope+unsubscr...@googlegroups.com.
>>> For more options, visit https://groups.google.com/d/optout.
>>>
>>> --
>>> --
>>> [CMLHope]
>>> A support group of http://cmlhope.com
>>> -------------------------------------------------
>>>
>>> You received this message because you are subscribed to the Google
>>> Groups "CMLHope" group.
>>> To post to this group, send email to CMLHope@googlegroups.com
>>> To unsubscribe from this group, send email to
>>> cmlhope-unsubscr...@googlegroups.com
>>> For more options, visit this group at
>>> http://groups.google.com/group/CMLHope
>>> ---
>>> You received this message because you are subscribed to the Google
>>> Groups "CMLHope" group.
>>> To unsubscribe from this group and stop receiving emails from it, send
>>> an email to cmlhope+unsubscr...@googlegroups.com.
>>> For more options, visit https://groups.google.com/d/optout.
>>>
>>> --
>>> --
>>> [CMLHope]
>>> A support group of http://cmlhope.com
>>> -------------------------------------------------
>>>
>>> You received this message because you are subscribed to the Google
>>> Groups "CMLHope" group.
>>> To post to this group, send email to CMLHope@googlegroups.com
>>> To unsubscribe from this group, send email to
>>> cmlhope-unsubscr...@googlegroups.com
>>> For more options, visit this group at
>>> http://groups.google.com/group/CMLHope
>>> ---
>>> You received this message because you are subscribed to the Google
>>> Groups "CMLHope" group.
>>> To unsubscribe from this group and stop receiving emails from it, send
>>> an email to cmlhope+unsubscr...@googlegroups.com.
>>> For more options, visit https://groups.google.com/d/optout.
>>>
>>> --
>>> --
>>> [CMLHope]
>>> A support group of http://cmlhope.com
>>> -------------------------------------------------
>>>
>>> You received this message because you are subscribed to the Google
>>> Groups "CMLHope" group.
>>> To post to this group, send email to CMLHope@googlegroups.com
>>> To unsubscribe from this group, send email to
>>> cmlhope-unsubscr...@googlegroups.com
>>> For more options, visit this group at
>>> http://groups.google.com/group/CMLHope
>>> ---
>>> You received this message because you are subscribed to the Google
>>> Groups "CMLHope" group.
>>> To unsubscribe from this group and stop receiving emails from it, send
>>> an email to cmlhope+unsubscr...@googlegroups.com.
>>> For more options, visit https://groups.google.com/d/optout.
>>>
>>>  --
>>> --
>>> [CMLHope]
>>> A support group of http://cmlhope.com
>>> -------------------------------------------------
>>>
>>> You received this message because you are subscribed to the Google
>>> Groups "CMLHope" group.
>>> To post to this group, send email to CMLHope@googlegroups.com
>>> To unsubscribe from this group, send email to
>>> cmlhope-unsubscr...@googlegroups.com
>>> For more options, visit this group at
>>> http://groups.google.com/group/CMLHope
>>> ---
>>> You received this message because you are subscribed to the Google
>>> Groups "CMLHope" group.
>>> To unsubscribe from this group and stop receiving emails from it, send
>>> an email to cmlhope+unsubscr...@googlegroups.com.
>>> For more options, visit https://groups.google.com/d/optout.
>>>
>>
>> --
>> --
>> [CMLHope]
>> A support group of http://cmlhope.com
>> -------------------------------------------------
>>
>> You received this message because you are subscribed to the Google Groups
>> "CMLHope" group.
>> To post to this group, send email to CMLHope@googlegroups.com
>> To unsubscribe from this group, send email to
>> cmlhope-unsubscr...@googlegroups.com
>> For more options, visit this group at
>> http://groups.google.com/group/CMLHope
>> ---
>> You received this message because you are subscribed to the Google Groups
>> "CMLHope" group.
>> To unsubscribe from this group and stop receiving emails from it, send an
>> email to cmlhope+unsubscr...@googlegroups.com.
>> For more options, visit https://groups.google.com/d/optout.
>>
>>  --
>> --
>> [CMLHope]
>> A support group of http://cmlhope.com
>> -------------------------------------------------
>>
>> You received this message because you are subscribed to the Google Groups
>> "CMLHope" group.
>> To post to this group, send email to CMLHope@googlegroups.com
>> To unsubscribe from this group, send email to
>> cmlhope-unsubscr...@googlegroups.com
>> For more options, visit this group at
>> http://groups.google.com/group/CMLHope
>> ---
>> You received this message because you are subscribed to the Google Groups
>> "CMLHope" group.
>> To unsubscribe from this group and stop receiving emails from it, send an
>> email to cmlhope+unsubscr...@googlegroups.com.
>> For more options, visit https://groups.google.com/d/optout.
>>
>
> --
> --
> [CMLHope]
> A support group of http://cmlhope.com
> -------------------------------------------------
>
> You received this message because you are subscribed to the Google Groups
> "CMLHope" group.
> To post to this group, send email to CMLHope@googlegroups.com
> To unsubscribe from this group, send email to
> cmlhope-unsubscr...@googlegroups.com
> For more options, visit this group at
> http://groups.google.com/group/CMLHope
> ---
> You received this message because you are subscribed to the Google Groups
> "CMLHope" group.
> To unsubscribe from this group and stop receiving emails from it, send an
> email to cmlhope+unsubscr...@googlegroups.com.
> For more options, visit https://groups.google.com/d/optout.
>
>  --
> --
> [CMLHope]
> A support group of http://cmlhope.com
> -------------------------------------------------
>
> You received this message because you are subscribed to the Google Groups
> "CMLHope" group.
> To post to this group, send email to CMLHope@googlegroups.com
> To unsubscribe from this group, send email to
> cmlhope-unsubscr...@googlegroups.com
> For more options, visit this group at
> http://groups.google.com/group/CMLHope
> ---
> You received this message because you are subscribed to the Google Groups
> "CMLHope" group.
> To unsubscribe from this group and stop receiving emails from it, send an
> email to cmlhope+unsubscr...@googlegroups.com.
> For more options, visit https://groups.google.com/d/optout.
>

-- 
-- 
[CMLHope]
A support group of http://cmlhope.com
-------------------------------------------------

You received this message because you are subscribed to the Google Groups 
"CMLHope" group.
To post to this group, send email to CMLHope@googlegroups.com
To unsubscribe from this group, send email to 
cmlhope-unsubscr...@googlegroups.com
For more options, visit this group at http://groups.google.com/group/CMLHope
--- 
You received this message because you are subscribed to the Google Groups 
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To unsubscribe from this group and stop receiving emails from it, send an email 
to cmlhope+unsubscr...@googlegroups.com.
For more options, visit https://groups.google.com/d/optout.

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