But is there also a productive IDE for 'the daily use'?
I still use Descent for Eclipse. It isn't maintained anymore but it's the only one with a copy of the dmd frontend with some semantic analysis. VisualD on Windows provides some basic auto-completion and goto definition etc via compiler generated json files.
I don't need a GUI-Designer (but it would be nice - maybe something like the QT-Designer)
I think QtD supports the Qt GUI Designer.
but a IDE which supports graphical debugging is vital for me
Then you should use VisualD on Windows. It includes cv2pdb which makes it possible to debug D apps with VisualStudio without much pain.