Check out:

   /Alexandre V. Mirgorodskiy and Barton P. Miller, "Diagnosing
   Distributed Systems with Self-Propelled Instrumentation",
   /ACM/IFIP/USENIX 9th International Middleware/, Leuven, Belgium,
   December 2008. /
   ftp://ftp.cs.wisc.edu/paradyn/papers/Mirgorodskiy08DistDiagnosis.pdf

   /Alexander V. Mirgorodskiy and Barton P. Miller, "Autonomous
   Analysis of Interactive Systems with Self-Propelled
   Instrumentation", /MMCN 2005: 12th Multimedia Computing and
   Networking/, San Jose, California, January 2005. /
   /ftp://ftp.cs.wisc.edu/paradyn/papers/Mirgorodskiy04SelfProp.pdf/

/--bart

/
On 2/19/2015 12:50 PM, Bill Williams wrote:
On 02/19/2015 10:25 AM, budchan chao wrote:

Also I was wondering if there was way to do the dynamic instrumentation
"in-band" if that makes sense. (Like using a separate thread in the same
process so that there is no need to have a separate mutator process to
do it.)

There have been various projects in the group over the years that do in-band (or first-party, as we refer to it) instrumentation. As far as I know, none of them have taken a separate thread approach. There's also Dyninst's binary rewriting mode, where the parsing/codegen/instrumentation process occurs once up-front and then you run the instrumented binary on its own.
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