On Wed, Aug 14, 2013 at 11:57:59PM -0400, John Clark wrote: > Russell Standish <li...@hpcoders.com.au> wrote: > > > > >>>[The central dogma of molecular biology] deals with the detailed > >>> states that such information cannot be transferred back from protein to > >>> either protein or nucleic acid. > >>> > >>> > >> >> I know of no example of a change in a protein making a systematic > >> repeatable change (as opposed to a random mutation) in the sequence of > >> bases in DNA that are passed onto the next generation. > >> > > > > > Epigenetic information is expressed by the presence or absence of > > methylation of the bases, not the sequence. > > > > A keen grasp of the obvious. So because information is not being > transferred from proteins to the base sequence of DNA I take it that you > are retracting your statement that epigenesis contradicts the central > dogma, not that it would matter because that is about molecular biology and > we're talking about Darwin and Evolution.
No - because the central dogma is about information being passed from the phenotype to the genotype. Even Crick's more restricted version doesn't mention nucleotide sequence - just information of the nucleic acid, and methylation of nucleotides is exactly that. > By the way, after the discovery > of prions a couple of decades ago we knew that sometimes hereditary > information can move from protein to protein and bypass DNA, so the central > dogma is not 100% true, just 98 or 99% true. > Yes, of course. Like pretty much all dogmas. And it took a generation of scientists before prion theory was accepted, another characteristic of a dogma. -- ---------------------------------------------------------------------------- Prof Russell Standish Phone 0425 253119 (mobile) Principal, High Performance Coders Visiting Professor of Mathematics hpco...@hpcoders.com.au University of New South Wales http://www.hpcoders.com.au ---------------------------------------------------------------------------- -- You received this message because you are subscribed to the Google Groups "Everything List" group. To unsubscribe from this group and stop receiving emails from it, send an email to everything-list+unsubscr...@googlegroups.com. To post to this group, send email to everything-list@googlegroups.com. Visit this group at http://groups.google.com/group/everything-list. For more options, visit https://groups.google.com/groups/opt_out.
