Hello,
I've become confused about the direction of the transformation specified
in the talairach.xfm file.

It seems that if you "manually" specify the --targ and --mov volumes in
conjunction with the --xfm option, that the "target" must be the
talairach average to get proper alignment:
e.g., 
tkregister2 --targ $FREESURFER_HOME/subjects/fsaverage/mri/T1.mgz --mov
orig.mgz --xfm transforms/talairach.xfm --reg tmp.dat

(The same targ/mov definition appears to be the case if you want to use
--lta to view a .lta transform instead).

However, the resulting output to the terminal for "Input registration
matrix" does not match the talairach.xfm file -- is there a matrix
inversion somewhere??

But, if you use the --fstal option
e.g., 
tkregister2 --s 020819_43 --fstal

then orig.mgz is now the "target" and the talairach average is now the
"movable" volume, and the output to the terminal for "Input registration
matrix" now exactly matches the values in the talairach.xfm file.  Based
on this, it seems that .xfm maps from mov to target (with orig.mgz being
the target).  However that doesn't seem consistent with the required mov
and targ specifications with using the --xfm flag directly...

thanks for clarifying,
Mike H.



-- 
Michael Harms, Ph.D.
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Conte Center for the Neuroscience of Mental Disorders
Washington University School of Medicine
Department of Psychiatry, Box 8134
Renard Hospital, Room 6615           Tel: 314-747-6173
660 South Euclid Ave.                Fax: 314-747-2182
St. Louis, MO 63110                  Email: [EMAIL PROTECTED]
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