In this case you would have six regressors:
1. control-offset
2. hiv-offset
3. control-age
4. hiv-age
5. control-ed
6. hiv-ed

If you want to test group thickness "regressing out" the effect of age
and ed, then you would just set the contrast to:

1 -1 0 0 0 0 0

Note that this will test it at age=0 and ed=0, which you may or may
not want to do. Ideally, you would test them at some age/ed in the
range of your sample. A lot of people simply demean each covariate,
but this can bias the results depending upon who you add or
remove. Better to choose an age/ed level independent of your sample.

doug



On Sat, 13 Jun 2009, Jeff Sadino wrote:


Hello Freesurfers,

My apologies for this very basic question more about statistics than 
freesurfer, but I have not found an answer anywhere on the wikis, or the web 
(maybe it is too basic :-) )  I am interested in age-related effects of hiv and 
I wanted to covary for age and education in mri_glmfit.  For example, if my 
fsgd file is:

class control
class hiv
variables age ed
input subj1 control 40 13
input subj2 hiv 35 12
...
...

and I use dods, is my contrast matrix the place where I would tell it to 
covary?  Something like:
0     0        -1     1           1     1                1     1
(y-int)     (age slope)   (covary for age)   (covary for ed)

As always, thank you for your help,
Jeff

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