Hi Jesse,

I doubt these have anything to do with talairach. Have you added control 
points? If not, I don't understand the cause of the local brightening that 
your images show in both the cerebellum and cortex in what is either the 
end of a white matter strand or in the gray matter itself.

cheers,
Bruce


On Fri, 22 Jan 2010, Jesse Bledsoe wrote:

> Hello FreeSurfer experts,
>
> I have been reconstructing many brains and noticed that the surfaces are
> quite bumpy. Here are a few things I have done to fix or understand more
> about the consistently bumpy surfaces I seem to generate after
> reconstruction:
>
> 1) Checked the talairach.xfm files with tkmedit and tkregister2 (it looked
> fine in all planes)
> 2) I have run mri_convert on original, talairach, and ac-pc aligned dicoms
> (Bruce, you were right, there did not appear to be any improvement from the
> original. Actually, the originals produced fewer surface errors).
>
> I have attached four .jpg images of white matter errors (bumps) in both
> tksurfer and tkmedit views with the same white matter points. Can you tell
> me if you see any errors in tkmedit that I am missing? I dont' seem to see
> any considerable pial/white matter inconsistencies yet continue to produce
> very bumpy surfaces. Also, why do some brains produce more bumps than
> others? I realize that a bad talairach may cause errors but my talairachs
> seem to be fine.
>
> Thanks in advance for all of your time,
>
> Jesse
>
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