Hi Karl,

you could try including average cortical thickness over the entire hemisphere as a covariate. This was Mike Harms' suggestion, and I think a good one.

cheers
Bruce


On Thu, 8 Apr 2010, Liukarl wrote:


Hello, Freesurfer experts:

I noticed for analyzing the results from autorecon2, the intracranial volume 
are controlled as covariate in some publications. Is there any corresponding 
covariate for cortical results from autorecon3, cortical thickness, surface, 
and volume?

In my current study, there are two group: one is a group with less optimal 
developmental environment and the other is control. I noticed that without any 
covariate, the r square from cortical measure and group variable was really 
low, only accounting for 2%. Is any standard way to analyze the cortical data?


Thanks!

Karl
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