Hi Kelly,

it's a bit of an open question what the relationshop between thickness 
and icv is. It's probably not linear, maybe icv^(1/3)?

cheers
Bruce



On Fri, 28 May 2010, Kelly Silva wrote:

> Hello,
>
> I'm doing regression analyses with cortical thickness at
> the level of voxel. Should I correct the total GM volume by introducing
> this parameter as a confounding variable? Shoud I include the
> intracranial volume as an additional nuisance variable?  If positive, I
> assume that these variables can only be introduced as covariates if
> they differ between groups. Am I correct?
>
> I saw in one message that we should not corret for thickness. Why not?
>
>                                            Thanks in advance and best regards,
>                                                                      Kelly
>
>
>
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