mapping the time courses to the average subject does not solve this 
problem, it just hides it. I'm not sure why this would be of a concern 
anyway. There might be a tiny difference in the expected variance for 
each subject, but, unless the region is very small, the differences 
won't amount for much.

doug

liang wang wrote:
> Dear Doug,
>
> Thanks for your comments. However, I am worried about the different 
> number of voxels within each parcellation between subjects, if 
> extracting fmri time course from individual parcellation result.
>
> Also, I am using the following combined commands to carry out the 
> steps. Do you think it's correct?
> reg-feat2anat --feat SUBID/bold.feat --subject SUBID
> aseg2feat --feat SUBID/bold.feat --aseg aparcs+aseg
> mri_segstats --seg 
> SUBID/bold.feat/reg/freesurfer/aparc.a2009s+aseg.nii.gz --in 
> filtered_fun_data.nii.gz -avgwf file.dat
>
> Thanks,
> Liang
>
> 2010/7/18 Doug Greve <gr...@nmr.mgh.harvard.edu 
> <mailto:gr...@nmr.mgh.harvard.edu>>
>
>
>     definitely use the individuals. Use mri_vol2surf to convert the motion
>     corrected (and otherwise unsmoothed) fmri time courses to the
>     surface. Then use mri_segstats with the  --avgwf and --annot options
>     to compute the mean time course over the parcellations.
>
>     doug
>
>
>
>
>     On Sat, 17 Jul 2010, liang wang wrote:
>
>         Hi,
>
>         Does anyone know one of studies which uses the parcellations
>         (aparc or
>         aparc.a2009s) Freesurfer provides to extract fMRI time course
>         from each
>         subject's fMRI data. Reading the instructions in Freesurfer
>         Wiki, I know how
>         to do that. However, I am not sure whether I should use the
>         parcellations
>         from the average output (obtained from make_average_subject),
>         or the
>         parcellations based on each subject. I would next compute
>         functional
>         connectivity between these regions. I am appreciated for any
>         suggestions.
>
>         Liang
>
>
>
>     -- 
>     Douglas N. Greve, Ph.D.
>     MGH-NMR Center
>     gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>
>     Phone Number: 617-724-2358
>     Fax: 617-726-7422
>
>     Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
>     <http://surfer.nmr.mgh.harvard.edu/fswiki/BugReporting>
>     FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html
>     <http://www.nmr.mgh.harvard.edu/facility/filedrop/index.html>
>
>
>
>     The information in this e-mail is intended only for the person to
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>
>
> -- 
> Liang Wang, PhD
> Postdoctoral Fellow
> Woodward Lab
> Department of Psychiatry
> University of British Columbia
> BC Mental Health & Addiction Services
> 938 West 28th Avenue
> Vancouver BC V5Z 4H4
> Telephone: 1-604-875-2000 (ext. 4735)
> Fax: 1-604-875-3871
> Email: wangl...@gmail.com <mailto:wangl...@gmail.com>
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-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358 
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html

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