perhaps an alternative is to use the surface area measure of an ROI,
namely the aparc regions, to conduct a group analysis, as the vertex
distribution problem is averaged-out over the region.

n.

On Wed, 2010-09-29 at 21:02 -0700, Don Hagler wrote:
> The area maps do contain the actual surface area of each vertex with
> units of mm^2.  The problem is that the area at a given vertex depends
> on how many vertices a given patch of cortex was divided into, which
> is initially uniform but then varies arbitrarily due to topology
> correction, rendering it useless for making statistical maps.
> 
> If you are interested in making statistical maps of between-group
> differences in surface area, the best way to do that is by calculating
> the areal expansion measure.  This is not a normally used feature of
> freesurfer, but is possible by using make_average_subject separately
> for each subject.
> 
> If you use the area values in the aparc stats files, those are the sum
> of area for all vertices in each parcellation, and they have units of
> surface area (unlike measures of areal expansion).
> 
> 
> > From: jsadino.que...@gmail.com
> > Date: Wed, 29 Sep 2010 15:57:38 -1000
> > To: freesurfer@nmr.mgh.harvard.edu
> > Subject: [Freesurfer] Surface Area and Cortical Volume
> > 
> > Hello,
> > 
> > As I understand it, the surface area measure is not a real surface
> > area measure. It is more a measure of how much the brain has to be
> > stretched in order to get into a common space. My question is that
> if
> > the cortical volume is calculated by multiplying the thickness and
> the
> > surface area (right?), then is it a real volume that can be compared
> > between subjects?
> > 
> > Also, is it is more accurate to use the cortical volume measures
> from
> > the aparc files rather than the aseg files, since the aseg files
> > overestimate the white matter due to the manual tracing it is based
> > on?
> > 
> > Thank you,
> > Jeff
> > _______________________________________________
> > Freesurfer mailing list
> > Freesurfer@nmr.mgh.harvard.edu
> > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
> > 
> > 
> > The information in this e-mail is intended only for the person to
> whom it is
> > addressed. If you believe this e-mail was sent to you in error and
> the e-mail
> > contains patient information, please contact the Partners Compliance
> HelpLine at
> > http://www.partners.org/complianceline . If the e-mail was sent to
> you in error
> > but does not contain patient information, please contact the sender
> and properly
> > dispose of the e-mail.
> > 
> _______________________________________________
> Freesurfer mailing list
> Freesurfer@nmr.mgh.harvard.edu
> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer

_______________________________________________
Freesurfer mailing list
Freesurfer@nmr.mgh.harvard.edu
https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer

Reply via email to