selxavg3-sess checks to see whether preproc has been run and runs it if 
it is needed, so all that stuff can go on in the background. It does 
look like the differences you are seeing come from the whitening. This 
attempts to account for temporal correlation in the noise. Whether you 
need it or not depends on what you actually report. If you report the 
volume of activation for each subject, then you'll probably want some 
sort of whitening. In general, people don't report this. If you are 
going to just hand the 1st level results up to the next higher level 
(eg, group analysis), then I don't think it makes a difference. A 
reviewer may balk if there has not been whitening performed at the first 
level, but this is usually just a misunderstanding on their part.

doug

Katie Bettencourt wrote:
> When I registered the 4.5 version, I did it fully manually, using 
> tkregister2, but with the version5 one I initially didn't do anything 
> outside of the commands I listed below (though the register.dat was 
> present from the 4.5 version), but then to check that I went through 
> and ran register-sess on the version 5, and then double checked it in 
> tkregister2 (as the output to register-sess suggested I do) and at 
> least at a coarse look it looked fairly well aligned, and rerunning 
> selxavg3-sess after running register-sess didn't change the output (in 
> fact, the picture I attached before was from the register-sess 
> version).  Does selxavg3-sess automatically run this registration in 
> version 5 or do you need to do the registration separately everytime? 
>  Similarly, I didn't run preproc-sess separately for version5, did I 
> need to?
>
> rerunning it with the -no-whiten flag seems to have pushed it in the 
> other direction.  I now get more activation in v5 than v4.5 (see 
> attached pictures)  which honestly I guess I like better... Do I need 
> to run it with the -no-whiten flag each time?  Exactly what is this 
> flag doing?
>
> Katie
>
> On Tue, Dec 7, 2010 at 2:20 PM, Douglas N Greve 
> <gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>> wrote:
>
>     Hmmm, not sure what's going on with that. Can you verify that the
>     registration is correct in the v5 results? The only other thing
>     that I can think of is that the whitening may be a bit different
>     between 4.5 and 5.0. Try turning off the whitening in v5
>     (-no-whiten when running mkanalysis-sess).
>
>     doug
>
>     Katie Bettencourt wrote:
>
>         I was attempting to run an analysis that was previously done
>         in freesurfer 4.5 in version 5 to see if I cuold switch over
>         to the new version.  However, I am getting very different
>         results for the two versions.  Below are the commands I ran in
>         both and attached are pictures of the differences.  I get much
>         much less activation (and much less than expected)  when using
>         version 5.  I assume this is because I've done something wrong
>         with the way I set up my version 5 analysis, but I don't knwo
>         what it is.  Any help would be appreciated.
>
>         version 5:
>         mkanalysis-sess -analysis supIPS-gamma-5rh -TR 1.5 -paradigm
>         supIPS.dat -event-related -runlistfile supIPSruns.txt -nskip 2
>         -nconditions 6 -gammafit 2.25 1.25  -surface self rh -fwhm 0
>         -refeventdur 6
>         mkcontrast-sess -analysis supIPS-gamma-5rh -contrast
>         act_vs_fix -a 1 -a 2 -a 3 -a 4 -a 5 -c 0
>         selxavg3-sess -s 101103TM_supIPS -df supIPS.dir -analysis
>         supIPS-gamma-5rh
>         tksurfer-sess -s 101103TM_supIPS -a supIPS-gamma-5rh-c
>         act_vs_fix -df supIPS.dir
>
>         version 4.5
>         mkanalysis-sess -analysis supIPS-gamma -TR 1.5 -paradigm
>         supIPS.dat -designtype event-related -funcstem fmc -motioncor
>         -runlistfile supIPSruns.txt -inorm -tpexclude tpexclude.dat
>         -nconditions 6 -gammafit 2.25 1.25 -noautostimdur
>         mkcontrast-sess -analysis supIPS-gamma -contrast act_vs_fix -a
>         1 -a 2 -a 3 -a 4 -a 5 -c 0
>         tksurfer-sess -s 101103TM_supIPS -df supIPS.dir -a
>         supIPS-gamma -c act_vs_fix -hemi rh
>
>
>         Katie
>
>         
> ------------------------------------------------------------------------
>
>
>         
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>
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>
>     -- 
>     Douglas N. Greve, Ph.D.
>     MGH-NMR Center
>     gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>
>     Phone Number: 617-724-2358 Fax: 617-726-7422
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-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358 
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
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