That worked, didn't work out that good for the significance of my data
though... :-(

Thanks, Doug & Mike!



On Wed, Mar 2, 2011 at 1:19 PM, Michael Waskom <mwas...@mit.edu> wrote:

> Hi Pieter,
>
> I think I may have run into this problem before by using mri_glmfit on
> a surface dataset and forgetting to to include --surf <subject>
> <hemi>.  The model fitting runs fine, but you end up with confusing
> problems at the corrections stage because the residual smoothness
> estimation doesn't work properly.  Do you happen to know whether you
> included --surf in your mri_glmfit call?
>
> Cheers,
> Mike
>
> On Sun, Feb 27, 2011 at 6:37 PM, Pieter van de Vijver <pvij...@gmail.com>
> wrote:
> > Dear Freesurfer experts,
> >
> >  I’m doing a longitudinal study on cortical thickness and subcortical
> > volumes and got some questions. I used the longitudinal stream for the
> > preprocessing
> >
> >
> >
> > 1.       On cortical thickness, I’m doing a paired analysis as described
> in
> > https://surfer.nmr.mgh.harvard.edu/fswiki/PairedAnalysis, and then a
> > cluster-wise correction as described in
> > https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/GroupAnalysis, with
> > 5000 simulations instead of 5, and a vertex-wise threshold of 3 .
> > But I don’t get the ocn.annot map, instead I get a ocn.mgh and ocn.lut.
> >  The CSD file also looks weird (constantly about 150 clusters with max
> size
> > one or 2) and the resulting cluster.summary also gives a huge list of
> very
> > small but significant clusters. Am I doing something wrong? How should I
> go
> > about this? I’m using FS 4.5. Files are included (jpg for sig.mgh and
> > cluster.mgh for negative simulation,  and csd (zipped), summary and
> > simulation log)
> >
> > 2.       For the subcortical volumetric analysis I use the aseg.stats. Is
> > the ICV a reliable measure to correct for overall brain size? I heard ICV
> > measurements are not very reliable on T1’s (I get a mean of 2,4% decrease
> > over 16 months...). Are other methods preferable to this one.
> >
> > 3.       Is there a logic or rule of thumb for choosing the vertex-wise
> > threshold?
> >
> >
> >
> > Thanks for your help!
> >
> >
> >
> > Pieter
> >
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> >
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>
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