Then, and finally is this method the best way to determine whether exist any cortical thickness anomaly, I mean, to use a normal control acquisition as comparisson?
Thanks in advance Ignacio. 2011/7/5 Bruce Fischl <fis...@nmr.mgh.harvard.edu> > Hi Ignacio, > > the thickness is definitely affected by factors such as sequence type, > field strength and acquisition parameters (not to mention age, maybe gender, > etc...) so I think you need to acquire your own control(s) on a matched > acquisition. > > cheers. > Bruce > > > On Tue, 5 Jul 2011, Ignacio Letelier wrote: > > Hi Bruce, >> >> Otherwise, is it possible to simply compare my T1 brain acquisition (with >> dysplasia suspicion) with a 'normal template' (which maybe bert) to >> determine whether there exist any anomaly in the cortical thickness ? >> and, >> is it possible to visualize these potential differences using a color map >> scaling? >> >> Thanks in advance- >> >> Best regards. >> >> Ignacio. >> >> 2011/7/3 Bruce Fischl <fis...@nmr.mgh.harvard.edu> >> Hi Ignacio, >> >> I see. You could do that, but I don't think it will show what >> you want. There is a big geometric component to the thickness - >> crowns are thick and fund are thin - so at the very least you >> might try including mean curvature as a covariate. >> >> >> cheers >> Bruce >> >> On Fri, 1 Jul 2011, Ignacio Letelier wrote: >> >> Sorry I didn't realize since you have the same domain. >> >> Ok, Let's say I do know the mean cortical thickness value >> of a subject. Then >> is it possible know what brain areas differ more from >> that mean value by >> using a color map visualization (I.e. for example: red = >> higher deviations, >> deep blue = lower deviations)? So this way I can determine >> where there may >> exist some kind of dysplasia. >> >> Best regards. >> >> 2011/7/1 Bruce Fischl <fis...@nmr.mgh.harvard.edu> >> can you post this kind of thing so others can answer? >> I still >> don't understand though. stdv of what? >> >> >> On Fri, 1 Jul 2011, Ignacio Letelier wrote: >> >> Let's say I want to know if there is a way to know >> where >> is the highest stdv in the same subject, using a >> color map >> visualization in qdec or something? >> >> Best regards. >> >> 2011/7/1 Bruce Fischl <fis...@nmr.mgh.harvard.edu> >> Hi Ignacio >> >> you mean different from the median in that >> subject? >> Easy enough to do in matlab, but we don't have >> anything >> out of the box to do it >> >> cheers >> Bruce >> >> On Fri, 1 Jul 2011, Ignacio Letelier wrote: >> >> Hi forum >> >> Is it possible to get statistical maps of >> cortical >> thickness differences in the same subject? I.e. to >> know >> what areas differ most from the median >> >> >> -- >> Ignacio >> >> >> >> >> The information in this e-mail is intended only for >> the >> person to whom it is >> addressed. If you believe this e-mail was sent to you >> in >> error and the e-mail >> contains patient information, please contact the >> Partners >> Compliance HelpLine at >> >> http://www.partners.org/**complianceline<http://www.partners.org/complianceline>. >> If the >> e-mail was >> sent to you in error >> but does not contain patient information, please >> contact >> the sender and properly >> dispose of the e-mail. >> >> >> >> >> >> >> >>
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