Regarding #2: Yes, if you a have global difference in thickness between groups, then it is appropriate to control for that in the same manner that one frequently controls for total brain volume in volumetric analyses.
cheers, -MH > Dear list, > > I have two question: > > 1. Is it possible to do the asymmetry analysis in FS, I mean to > compare left and right hemispheres within one group? > > 2. Is it necessary to somehow control for global abnormality of > thickness while looking at regional abnormality, e.g. if one group has > thinner brain overall, but also thinner brain in some regions? > (Similar to dividing by total brain volume in volumetric analysis) > > Thank you and best wishes, > Tanja. > _______________________________________________ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > > The information in this e-mail is intended only for the person to whom it > is > addressed. If you believe this e-mail was sent to you in error and the > e-mail > contains patient information, please contact the Partners Compliance > HelpLine at > http://www.partners.org/complianceline . If the e-mail was sent to you in > error > but does not contain patient information, please contact the sender and > properly > dispose of the e-mail. > _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer