Thanks Sebastian and Doug, that clears everything up.

-Clark


On Sep 26, 2011, at 11:27 AM, Douglas N Greve wrote:

> 
> 
> Clark Fisher wrote:
>> Hi Doug,
>> 
>> Thanks for pointing me back to that; I had forgotten how much depth it 
>> goes into!  I have 2 remaining questions:
>> 
>> 1) Why is the tkr vox2ras transform sometimes dramatically different 
>> from the one in the volume header?  For instance, in one of the 
>> functional volumes I'm talking about, "mri_info --vox2ras" gives:
>> 
>> -3.42822    0.21499    0.15398  101.74103 
>>  -0.24476   -3.27187   -1.19314  135.02863 
>>   0.06182   -1.03201    3.81480  -30.98481 
>>   0.00000    0.00000    0.00000    1.00000 
>> 
>> while "mri_info --vox2ras-tkr" gives:
>> 
>> -3.43750    0.00000    0.00000  110.00000 
>>   0.00000    0.00000    4.00000  -70.00000 
>>   0.00000   -3.43750    0.00000  110.00000 
>>   0.00000    0.00000    0.00000    1.00000 
>> 
>> I would understand if the tkr-vox2ras only did flips and 90º rotations 
>> to put the data as close to RAS format as possible without having to 
>> interpolate, but the orientations produced by those 2 transformations 
>> are very different, with the rows and the slices essentially switched. 
>> I would guess that it has something to do with this explanation from 
>> Slide 5, but I don't quite understand it:
>> 
>> "Field-of-View based – only depends on the identity of columns, rows, 
>> and slices, the number of voxels in each dimension, and their sizes. 
>> Unrelated to the “true” geometry but is an RAS coordinate system when 
>> the volume is “Coronally” sliced, which is the based “conformed” 
>> orientation in FreeSurfer."
>> 
>> Any additional clarity you could provide would be appreciated.
> The tkr vox2ras is not related to RAS/LIA/etc and you should not attempt 
> to understand it using these terms. It will always have the same pattern 
> of zeros and non-zeros regardless of the true geometry. Given the number 
> of voxels in each dimension and the voxel size in each dimension, one 
> can write down the tkr vox2ras without knowing anything else above the 
> volume. This unfortunate situation is historical. The true geometry as 
> it relates to the tkr geometry ends up being embedded in the 
> registration matrix. In the end, neither the tkr vox2ras nor the 
> registration matrix are interpretable by themselves (but together they are).
>> 
>> 2) In Freesurfer XYZ space, why are the volumes centered at (# of 
>> voxels)/2?  I would think that centering at ((# of voxels) + 1) /2 
>> would put the true center of the volume on the origin.
> You are correct. This is another unfortunate accident of history.
> doug
>> 
>> Thanks again,
>> Clark
>> 
>> On Sep 20, 2011, at 2:14 PM, Douglas N Greve wrote:
>> 
>>> Hi Clark, have you looked at this documentation yet?
>>> http://www.freesurfer.net/fswiki/CoordinateSystems?action=AttachFile&do=get&target=fscoordinates.ppt
>>>  
>>> <http://www.freesurfer.net/fswiki/CoordinateSystems?action=AttachFile&do=get&target=fscoordinates.ppt>
>>> doug
>>> Clark Fisher wrote:
>>>> Hello,
>>>> 
>>>> I was wondering what orientation conventions are used when 
>>>> calculating the affine transformation matrix in register.dat.  For 
>>>> an example, I'll use the data from subject 101 of the fsfast 
>>>> tutorial. According to mri_info, the functional volume is in LPS 
>>>> orientation, and the processed anatomical volume (T1.mgz) is in LIA 
>>>> orientation. Does the matrix in register.dat convert from the 
>>>> functional LPS orientation to the anatomical LIA orientation, or 
>>>> does the matrix assume these volumes are already transformed in some 
>>>> other way?
>>>> 
>>>> Thanks,
>>>> Clark
>>>> _______________________________________________
>>>> Freesurfer mailing list
>>>> [email protected]
>>>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>>> 
>>>> 
>>>> 
>>> 
>>> -- 
>>> Douglas N. Greve, Ph.D.
>>> MGH-NMR Center
>>> [email protected]
>>> Phone Number: 617-724-2358
>>> Fax: 617-726-7422
>>> 
>>> Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
>>> FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html
>>> 
>>> 
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>> 
> 
> -- 
> Douglas N. Greve, Ph.D.
> MGH-NMR Center
> [email protected]
> Phone Number: 617-724-2358 
> Fax: 617-726-7422
> 
> Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
> FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html
> 


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