Hi Paolo, I don't think we have have any tools to apply a matrix to a 
trk file. Or maybe I'm wrong?
doug

paolo wrote:
> Bruce, Doug, Thomas, thank you so much, things are getting slowly
> clearer now 
>
> I can try to explain better what i want to do, so that perhaps
> it will be easier for you too to tell what is the best way
> to approach this problem
>
> essentially we have a number of subjects, with already extracted
> white matter fiber tracts (in .trk format)
> The idea was to transform these  fibers back to freesurfer space (is
> it the talairach space? in any case, is this what happens by using the
> talairach.xfm matrix?), and then compare them in this space, as, i would
> guess, there is still some sort of deviation from the standard fiber
> pathway.
>
> Is this unreasonable?
>
> also, just for visualization purposes, i was thinking of rendering
> these fibers in their context, but the average brain is, as you point
> out, a bit too blurry.
> Would it make sense here to bring something like MNI152 into the
> freesurfer space, and use this one (and its segmentation) instead of the
> fsaverage as an illustrative atlas in freesurfer space?
>
> Paolo
>
>
>
> On Mon, 7 Nov 2011 11:41:46 -0500 (EST)
> Bruce Fischl <fis...@nmr.mgh.harvard.edu> wrote:
>
>   
>> Hi Paolo,
>>
>> Are you showing individual subject data in the MNI space, or group
>> average data? In general showing template brains and average data is
>> not a good idea. It misrepresents the spatial localization accuracy
>> of the data. You should try to use averages of the anatomy for groups
>> of tracts of average fmri data or other group stats/data.
>>
>> cheers
>> Bruce
>>
>> On Mon, 7 Nov 2011, Paolo wrote:
>>
>>     
>>> I think it is well possible.
>>> And in principle i just wanted to use it for presentation, but the
>>> fsaverage doesnt really look like a "template" brain, rather like
>>> an average
>>>
>>> that's why i was wondering whether there is a more realistic
>>> template available in freesurfer space, or how i can create one
>>> (the idea was to recon-all the MNI152, which to me resembles much
>>> more to a brain)
>>>
>>> would it be the correct approach, or do you have other suggestions?
>>> by the way is it normal that recon-all on mni152 takes just ages to
>>> complete? (>12 hours on an athlon64, dont know exactly how long, i
>>> always stopped it before it finished)
>>>
>>> Paolo
>>>
>>>
>>> On 07-Nov-11 16:03, Thomas Yeo wrote:
>>>       
>>>> I am probably wrong, but doesn't the volumetric part of fsaverage
>>>> correspond to MNI305 space rather than MNI152 space?
>>>>
>>>> --Thomas
>>>>
>>>> On Mon, Nov 7, 2011 at 9:00 AM, Bruce
>>>> Fischl<fis...@nmr.mgh.harvard.edu>  wrote:
>>>>         
>>>>> Hi Paolo,
>>>>>
>>>>> I think fsaverage has this in the aseg.mgz.
>>>>>
>>>>> cheers
>>>>> Bruce
>>>>> On Mon, 7 Nov 2011, Paolo wrote:
>>>>>
>>>>>           
>>>>>> In the meanwhile i did some research, and it looks like
>>>>>> freesurfer does not use MNI152 as default template, am i right?
>>>>>> it seems that the default template is the fsaverage subject,
>>>>>> which in fact does not look like very realistic.
>>>>>>
>>>>>>
>>>>>> Is there any way to get a realistic brain&  segmentation that is
>>>>>> "idealized" enough, and still in talairach space (freesurfer
>>>>>> space)?
>>>>>>
>>>>>> maybe the MNI152 after recon-all and mri_transform to apply back
>>>>>> the transformation?
>>>>>>
>>>>>> i am sorry if these questions look unreasonable, i am new of
>>>>>> freesurfer, and still have problem orienting myself in the
>>>>>> documentation :)
>>>>>>
>>>>>> best,
>>>>>> Paolo
>>>>>>
>>>>>> On 05-Nov-11 00:57, Paolo wrote:
>>>>>>             
>>>>>>> Hello
>>>>>>>
>>>>>>> I am a new user of freesurfer.
>>>>>>> I was wondering whether the brain regions for the MNI152
>>>>>>> dataset are available anywhere (i mean the template brain
>>>>>>> regions for the default MNI152 template).
>>>>>>>
>>>>>>>
>>>>>>> I have also another question: i have the dti fiber tracts
>>>>>>> extracted and computed and already in .trk format.
>>>>>>> I was wondering: to bring them back into the template MNI152
>>>>>>> space, is it sufficient to apply the talairach.xfm
>>>>>>> transformation matrix to the vertex data, or do i also need to
>>>>>>> use the m3z files (which look like a nonlinear deformation
>>>>>>> field)?
>>>>>>>
>>>>>>> thanks in advance!
>>>>>>> Paolo
>>>>>>>               
>
>
>
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>   

-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
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Fax: 617-726-7422

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