Hi Catherine,

it shouldn't be necessary, but you should be very careful that any effects you find are biological ones and don't simply reflect acquisition differences.

cheers
Bruce
On Wed, 14 Dec 2011, Cat Chong wrote:

Dear Experts,

I am sorry for the basic question but we have a dataset of subjects we  like
to analyze for which  we have different slice thicknesses and orientations
in dicom format. All T1's  collected were SPGR volumes with the same scanner
parameters.
My question was: Do you advice to re-orient and re-slice the dataset to make
it uniform or is that step not necessary

cheers and thank you
catherine

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