Dear Lilla I appreciate your answers. It was very helpful. Just another follow-up question. I think freesurfer itself ended without errors and the skull-stripped and surfaces look okay. I think in the recommended reconstruction Pipeline, "check segmentation" is related to checking atlas worked. Still, I wonder there is a gold standard to check the atlas (Deksian atlas) works okay. .
Thanks again! Best Cheol Cheol Han, Ph.D Computational Neuroscience and Neuroinformatics Department of Brain and Cognitive Sciences Seoul National University Korea On Fri, Mar 30, 2012 at 2:46 AM, Lilla Zollei <lzol...@nmr.mgh.harvard.edu>wrote: > > Hi Cheol, > > > I am using freesurfer for patients with various neural disease. I wonder >> the the >> freesurfer atlas is applicable to them: dementia (with Lewy bodies, DLB), >> epilepsy, schizophrenia, ADHD, Alzheimer, stroke. (I know some studies >> already >> used freesurfer for some of the diseases in the list,) I believe epilepsy >> patients with lobectomy cannot be applicable. >> > > If the malformation or the difference between normal control acquisitions > and your scans is significant the FS pipeline, using the FS atlas is not > going to be successful. Withuot seeing your data I cannot tell which > population from the above is going to be affected, but if in doubt just try > processing one or two representative samples from the different populations > and assess how successful the processing is. > > > Also is there age limit for the freesurfer atlas? How young can the atlas >> work >> for? 4 year-old? 6 year-old? or more than 10 year-old? How about the upper >> bound? 80 year-old? >> > > The lower bound, in our experience, is about 4-5 yrs. Of course, it > depends on your data quality but we had success all the way down to that > age. I am not aware of any upper limits. Again, if you are processing these > kind of "extreme" populations, make sure that you inspect the outcome of > the FS recon pipeline carefully before proceeding with any type of analysis. > > Lilla > > > The information in this e-mail is intended only for the person to whom it > is > addressed. If you believe this e-mail was sent to you in error and the > e-mail > contains patient information, please contact the Partners Compliance > HelpLine at > http://www.partners.org/**complianceline<http://www.partners.org/complianceline>. > If the e-mail was sent to you in error > but does not contain patient information, please contact the sender and > properly > dispose of the e-mail. >
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