hi miro, as per me, i would suggest to divide ICV with TotalGrayVol and other aseg.stats files' global measures to remove the invariability across these measures. divide ICV to totalgrayvol,corticalwhitemattervolume,supratenorialvol,subcorticalgrayvol...this will remove any in-variability within those measures across ICV......
hope that helps kk ----- Original Message ----- From: "Miro Drahos" <[email protected]> To: [email protected] Sent: Thursday, June 21, 2012 2:21:13 PM Subject: [Freesurfer] correcting for normal inter-cranial variability Hi all, When analyzing output measures from FreeSurfer, what is the proper way to correct for normal anatomical variability before comparing between subjects? Which variable should be used to calculate normalized measures? volumetric measures -- total intra-cranial volume? total brain volume? surface measures -- total surface area? thickness measures -- mean thickness? Thank you! Miro Drahos _______________________________________________ Freesurfer mailing list [email protected] https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. _______________________________________________ Freesurfer mailing list [email protected] https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
