Hi Freesurfers, My experimental design includes 3 discrete factors and 1 continuous variables:
Discrete factors: diagnosis with two levels (A, B); genotype with two levels (G, T); gender (F, M) Continuous variable: age So I can get 8 classes: AGF, AGM, ATF,ATM, BGF, BGM, BTF, BTM. Then I want to perform 2 (diagnosis)* 2(genotype) interaction analysis with regressing out the effect of gender and age. Is the following contrast matrix correct? 0.25 0.25 -0.25 -0.25 -0.25 -0.25 0.25 0.25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.25 0.25 -0.25 -0.25 -0.25 -0.25 0.25 0.25 Any help will be very appreciated. Best wishes, Meng
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