Use the significant clusters as ROIs doug On 09/07/2012 10:43 AM, Meng Li wrote: > Hi professor, > Thanks for your letter. > When I perform the analysis of interaction by using the matrix： > 0.25 0.25 -0.25 -0.25 -0.25 -0.25 0.25 0.25 0 0 0 0 0 0 0 0 0 0 0 0 0 > 0 0 0 > I get the significant clusters which have interaction. Then I do post > hoc analysis, that is, I want to analyze the effect of two genotype on > the A group (or B group), should I use the significant clusters as > ROIs, or analyze on the whole brain directly? > > At 2012-09-07 22:12:25,"Douglas N Greve"<gr...@nmr.mgh.harvard.edu> wrote: > > > >That is the correct matrix to use. You can create a new FSGD file (and > >the second matrix would be correct for it), but you do not have to. It > >will save you a few degrees of freedom. > >doug > > > > > > > >On 09/07/2012 05:49 AM, Meng Li wrote: > >> Hi professor, > >> Thanks for your reply. > >> When I perform the main effect of dignosis, is the following matrix I > >> used correct? > >> 0.25 0.25 0.25 0.25 -0.25 -0.25 -0.25 -0.25 0 0 0 0 0 0 0 0 0 0 0 0 0 > >> 0 0 0 (I think it regressed out the effect of genotype and gender, > >> that is it takes the genotype as a covariable) > >> > >> Or I should create another fsgd file, that has 4 classes: AF, AM, BF, > >> BM. And I can use the matrix (0.5 0.5 -0.5 -0.5 0 0 0 0 0 0 0 0) to > >> perform the main effect of diagnosis. > >> Which one of two mentioned matrix is right? > >> Thanks a lot. > >> Best wishes > >> Meng > >> > >> > > > >-- > >Douglas N. Greve, Ph.D. > >MGH-NMR Center > >gr...@nmr.mgh.harvard.edu > >Phone Number: 617-724-2358 > >Fax: 617-726-7422 > > > >Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting > >FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html > > > > > > > >The information in this e-mail is intended only for the person to whom it is > >addressed. If you believe this e-mail was sent to you in error and the e-mail > >contains patient information, please contact the Partners Compliance > >HelpLine at > >http://www.partners.org/complianceline . If the e-mail was sent to you in > >error > >but does not contain patient information, please contact the sender and > >properly > >dispose of the e-mail. > >
-- Douglas N. Greve, Ph.D. MGH-NMR Center gr...@nmr.mgh.harvard.edu Phone Number: 617-724-2358 Fax: 617-726-7422 Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
