Hi Angela

negative sulc implies gyral, but there must be positive sulc also, no? 
When you overlay sulc on an individual subject to you see red (positive) as 
well as green (negative)?

cheers
Bruce


On Mon, 4 Feb 2013, 
angela.fav...@unipd.it wrote:

> Dear experts,
> I am studying a group of patients with a genetic illness that implies
> alterations of olfactory tracts and sulci. My aim was to explore the depth
> of the olfactory sulci in both patients and controls.
> I draw a ROI following the image of the sulcus in the fsaverage (see the
> figure) and I extracted measures of 'sulc' and 'thickness' for any subject
> using this ROI.
>
> My problem is that I found only zero or negative values for sulc (also in
> controls!). This means that there is not a sulcus, but a gyrus? The
> difference is statistically significant between patients (more negative)
> and controls (around zero or low negative).
>
> What is the problem and how can I measure the depth of the sulcus? Perhaps
> should I work on an 'average' surface based on my healthy controls? How
> can I obtain it?
>
> Thank you for any help!
>
> Angela
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