Hi,

I have been working on a DBM based method to obtain longitudinal atrophy on
some brain data. To quantify ROI, i use aseg.mgz. Several papers talk about
Whole Brain, ventricular atrophy but do not actually define what
substructures they use? It will be great if somebody can help me get the
actual definition of whole brain and ventricles. For ex: WM Hypointensities
are part of whole brain?, Since they increase in volume.

Thank you ,

Akshay
University of Copehagen
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