Hi Dusan
the one significant confound that you have to worry about is subject
motion being substantially more in your patient population. You might try
rating them for motion blinded to group and see if there is an inbalance.
cheers
Bruce
On Sun, 17 Mar
2013, Dusan Hirjak wrote:
Dear FreeSurfer experts,
we did a FreeSurfer-Analysis of cortical thickness in schizophrenia patients
with motor abnormalities and
found significant changes of cortical thickness in many brain regions. The Qdec
p-maps showed many regions with
surface size exceeding 100mm2. We used a 15mm FWHM smoothing.
Does anabody have an idea if there is a reasonable neurobiological/ontological
basis/explanation for this finding?
What is the exact size of M1 and SMA in mm2?
Thank you for your time!
Dusan
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