Hi,
Sorry, but I don't understand what you're asking.

-MH

-- 
Michael Harms, Ph.D.
-----------------------------------------------------------
Conte Center for the Neuroscience of Mental Disorders
Washington University School of Medicine
Department of Psychiatry, Box 8134
660 South Euclid Ave. Tel: 314-747-6173
St. Louis, MO  63110 Email: mha...@wustl.edu

From:  <std...@virgilio.it>
Reply-To:  <std...@virgilio.it>
Date:  Thursday, April 4, 2013 9:31 AM
To:  <freesurfer@nmr.mgh.harvard.edu>
Subject:  [Freesurfer] R: Re:  cortical thickness normalization

Thank you very much, Michael!

I have just an other important question, please.

I'm performing cortical thickness analysis on three groups. One of this is a
control group and I'm using it as support because I'm interested only to
difference between the two groups of disease.

These are my questions:

1- Is correct if I'm applying qdec, testing before a) disease 1 vs disease
2; b) controls vs disease 1 and c) controls vs disease 2.

2- Addictionally to cortical thickness that I'm reporting always as nuisance
factor in qdec,  I'd test some covariates.

Taking in account my study design, could I test each covariates separately
on my model using qdec?

Thanks,


Stefano

----Messaggio originale----
Da: mha...@conte.wustl.edu
Data: 4-apr-2013 15.45
A: <std...@virgilio.it>, <freesurfer@nmr.mgh.harvard.edu>
Ogg: Re: [Freesurfer] cortical thickness normalization

If you're studying thickness, I'm a fan of using mean cortical thickness as
the covariate (since thickness is what you're studying).  I've posted on
this in the past.

cheers,
-MH

-- 
Michael Harms, Ph.D.
-----------------------------------------------------------
Conte Center for the Neuroscience of Mental Disorders
Washington University School of Medicine
Department of Psychiatry, Box 8134
660 South Euclid Ave. Tel: 314-747-6173
St. Louis, MO  63110 Email: mha...@wustl.edu

From:  <std...@virgilio.it>
Reply-To:  <std...@virgilio.it>
Date:  Thursday, April 4, 2013 7:21 AM
To:  <freesurfer@nmr.mgh.harvard.edu>
Subject:  [Freesurfer] cortical thickness normalization

Hi list,

I'm reading a lot of post on this list about cortical thickness
normalization. 

I' m noting very different results on my data when I use mean thickness or
ICV as nuisance factor than no factor.

I'm confuse on this topic, could you advise the best way, please?

Thanks,


Stefano
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