yes
On 06/03/2013 02:26 PM, Fotiadis, Panagiotis wrote:
> I see. Would it be correct to say that better kurtosis would be illustrated 
> as less significant clusters in the kurtosis.mgh overlay?
>
> Panos
> ________________________________________
> From: freesurfer-boun...@nmr.mgh.harvard.edu 
> [freesurfer-boun...@nmr.mgh.harvard.edu] on behalf of Douglas N Greve 
> [gr...@nmr.mgh.harvard.edu]
> Sent: Monday, June 03, 2013 1:53 PM
> To: freesurfer@nmr.mgh.harvard.edu
> Subject: Re: [Freesurfer] Group Analysis Question
>
> Not necessarily. It could have been in the FS analysis. You can run
> mri_glmfit with  --kurtosis (a hidden option). This will create a
> kurtosis.mgh and pkurtosis.mgh. Kurtosis is a measure of gaussianity of
> the residuals (larger being less gaussian). The pkurtosis the the sig
> (-log10(p)) of the probability of seeing the kurtosis under the null
> (ie, the residuals are gaussian). So you can see if one model gives you
> better kurtosis than another.
>
> doug
>
>
> On 06/03/2013 01:20 PM, Fotiadis, Panagiotis wrote:
>> I see. Yes from the one hand the results that I got make a lot more sense in 
>> the second type of analysis, compared to the first one, however, there are 
>> some somewhat important difference between the two analyses. If there is an 
>> issue with the data, do you believe that it would be in the acquisition? 
>> Because I checked the reconstructions and they look fine.
>>
>> Thanks,
>> Panos
>> ________________________________________
>> From: freesurfer-boun...@nmr.mgh.harvard.edu 
>> [freesurfer-boun...@nmr.mgh.harvard.edu] on behalf of Douglas Greve 
>> [gr...@nmr.mgh.harvard.edu]
>> Sent: Monday, June 03, 2013 11:24 AM
>> To: freesurfer@nmr.mgh.harvard.edu
>> Subject: Re: [Freesurfer] Group Analysis Question
>>
>> I would not expect them to be identical but similar.  If they change a
>> lot there may be an issue with your data.
>> doug
>>
>>
>>
>> On 6/3/13 11:11 AM, Fotiadis, Panagiotis wrote:
>>> Hey Doug,
>>>
>>> I have run a group analysis on my data with two different ways. (The input 
>>> is cortical thickness.) In the first analysis, I specified 4 groups 
>>> (Diseased_Male, Diseased_Female, Healthy_Male, and Healthy_Female) whereas 
>>> in the second, just two groups (Diseased, Healthy). One of the comparisons 
>>> that I did was the age slope between Diseased and Healthy. Therefore in the 
>>> first analysis, I set the contrast vector to be [0 0 0 0 0.5 0.5 -0.5 -0.5] 
>>> and in the second analysis I set it to [0 0 1 -1]. However, the results 
>>> that came up were somewhat different. For instance there were clusters in 
>>> the second analysis that were significant but were not significant in the 
>>> first analysis.
>>> Shouldn't the results be the same?
>>>
>>> Thank you,
>>> Panos
>>> _______________________________________________
>>> Freesurfer mailing list
>>> Freesurfer@nmr.mgh.harvard.edu
>>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>>
>>>
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>> Freesurfer@nmr.mgh.harvard.edu
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>>
>>
> --
> Douglas N. Greve, Ph.D.
> MGH-NMR Center
> gr...@nmr.mgh.harvard.edu
> Phone Number: 617-724-2358
> Fax: 617-726-7422
>
> Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
> FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
> www.nmr.mgh.harvard.edu/facility/filedrop/index.html
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>
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> _______________________________________________
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> Freesurfer@nmr.mgh.harvard.edu
> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>
>

-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
www.nmr.mgh.harvard.edu/facility/filedrop/index.html
Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/

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