Dear Freesurfer experts,

I have been using Freesurfer in combination with rtview.sh to visualize my 
retinotopic mapping results (rotating wedge) and to define masks for individual 
visual areas. The command that I use for this is something like:

rtview.sh --s *subj_id* --lh --polar --real polar/real.nii.gz --imag 
polar/imag.nii.gz --fsig polar/fsig.nii.gz 

I was under the impression that by specifying fsig, Freesurfer would internally 
threshold the resulting polar map according to an F-test to show only 
significant vertices. Is this true?

I actually doubt that this is the case because I noticed in the "configure 
overlay display" that the maps are seemingly arbitrarily thresholded at a "Min" 
of 0.4. Is this threshold derived based on statistical principle?

How can I do proper statistics with fsig.nii.gz in Freesurfer, i.e. define 
alpha, correct for multiple comparisons etc.?

Thanks,
Michael

P.S.: Just to provide some context for my question... imho it doesn't matter 
much if a given vertex is significantly activated if the only purpose is to 
define boundaries between visual areas. However, an exception would be the 
definition of such boundaries in the cortical surface near the fovea where 
boundaries between areas cannot be identified as reliably as in more eccentric 
regions. I was thinking that by focusing only on significant vertices, I would 
be able to isolate only those voxels that can clearly be assigned to a single 
visual area - even if that means that I may have to discard some vertices near 
the fovea. 

--
Michael Bannert, Dipl.-Psych.
Vision & Cognition Lab, Centre for Integrative Neuroscience, Univ. of Tübingen 
& BCCN Tübingen
Otfried-Müller-Str. 25, 72076 Tübingen, Germany
Phone: +49 - (0)7071 / 29 - 89031



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