I don't know, but I'm pretty sure the Freesurfer team will recommend you use 
v5.3.0. There are emails saying as much.
Chris
________________________________________
From: freesurfer-boun...@nmr.mgh.harvard.edu 
[freesurfer-boun...@nmr.mgh.harvard.edu] on behalf of clarissa yasuda 
[clayas...@gmail.com]
Sent: Thursday, July 25, 2013 12:54 AM
To: freesurfer@nmr.mgh.harvard.edu
Subject: [Freesurfer] different results between 5.1.0 and 5.2.0

Dear FreeSurfer Experts

As in some other posts, I have also observed some differences between the two 
releases.  The values from cuneus (thickness) are similar to the post from 
Ritobrato Datta, Ph.D. on 18 march.

 But I also observed some differences in volume of right / left thalami. Did 
anybody observe such asymmetry??
I am now running analysis with patients and controls on data from 5.2.0 and got 
surprised with this asymmetry.

Here I am showing the average I obtained:

        R PALLIDUM      L PALLIDUM       R THAL L THAL          RH_CUNEUS       
LH_CUNEUS
5.1 (350 SUBJECTS)      1580    1688     6701   6970.31         1.845   1.857

5.2 (115 SUBJECTS, subgroup of 350)     1519    1367                    6520    
7401            2.42    2.40

Is there any approach to correct it on 5.2 ??
Thanks in advance
clarissa

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