Thank you very much for your answer Bruce ! have a nice evening,
Alex. Le 3 juin 14 7:6, Bruce Fischl a écrit : > Hi Alex > > I would think that longitudinal analysis is still the way to go as we try > to improve both reliability and sensitivity using the fact that we have > multiple scans/subject. > > cheers > Bruce > On Tue, 3 Jun 2014, Alexandru Hanganu wrote: > >> Hello Everyone, >> >> could someone please give us an advice about which method you consider is >> the best for our study ? >> >> we have two groups with MRI at Time 1. Each group received medication. After >> this we performed another MRI at Time 2 after 2 weeks. >> >> The best method for this study is a longitudinal one or a cross-sectional >> GLM ? >> >> We consider that the distance between the time points is too small, and the >> longitudinal method is not the best choice. Hence, this study should be >> treated as a cross-sectional one. In this case we think about performing a >> simple GLM with the contrasts: >> 0.5 0.5 0.5 0.5 >> or 1 -1 -1 1 >> >> for the groups: >> 1) grp 1 time 1 >> 2) grp 1 time 2 >> 3) grp 2 time 1 >> 4) grp 2 time 2 >> >> we are searching to see whether medication had any impact on the cortical >> morphology in each group and between the groups. >> >> Thank you ! >> Best regards, >> Alex. >> >> > _______________________________________________ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > > The information in this e-mail is intended only for the person to whom it is > addressed. If you believe this e-mail was sent to you in error and the e-mail > contains patient information, please contact the Partners Compliance HelpLine > at > http://www.partners.org/complianceline . If the e-mail was sent to you in > error > but does not contain patient information, please contact the sender and > properly > dispose of the e-mail. > > _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
