Hi Panos, It all depends on what your question is: whether the between-group difference in LGI and surface area is an absolute difference (then don't correct), or whether you want to see if it holds after correction. In any case, by geometric definition, the relationship between surface area, and thus LGI, and volume is governed by a power law, which means that if you linearly correct for intracranial volume, some of its effect will remain.
Hope it helps, Marie On Jul 10, 2014, at 10:57 AM, <pfot...@nmr.mgh.harvard.edu> wrote: > Hi FS Community, > > I was wondering whether LGI and Surface Area need to be corrected for > total Intracranial Volume. > > Thanks in advance, > Panos > _______________________________________________ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > > The information in this e-mail is intended only for the person to whom it is > addressed. If you believe this e-mail was sent to you in error and the e-mail > contains patient information, please contact the Partners Compliance HelpLine > at > http://www.partners.org/complianceline . If the e-mail was sent to you in > error > but does not contain patient information, please contact the sender and > properly > dispose of the e-mail. > _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
