Hi both,

That makes sense, however, as for my groups, all exceed 10 cases per 
combination  for gender and scanner type (two dichotomous variables).
But I also use Follow-time and age as covariate, might I need to recode those, 
to less unique combinations are possible?

Thanks.

Sander 

-----Oorspronkelijk bericht-----
Van: freesurfer-boun...@nmr.mgh.harvard.edu 
[mailto:freesurfer-boun...@nmr.mgh.harvard.edu] Namens Sanne Oostermeijer
Verzonden: donderdag 7 mei 2015 10:02
Aan: freesurfer@nmr.mgh.harvard.edu
Onderwerp: Re: [Freesurfer] FW: Re: ERROR: matrix is ill-conditioned or badly 
scaled

Hi Doug, I did. The email below is another FS user having the same error.

Sander, I had the same problem due to having only 1 female in one of the groups 
(and correcting for gender).

-----Oorspronkelijk bericht-----
Van: freesurfer-boun...@nmr.mgh.harvard.edu 
[mailto:freesurfer-boun...@nmr.mgh.harvard.edu] Namens Douglas N Greve
Verzonden: woensdag 6 mei 2015 17:47
Aan: freesurfer@nmr.mgh.harvard.edu
Onderwerp: Re: [Freesurfer] FW: Re: ERROR: matrix is ill-conditioned or badly 
scaled

did you see the email I sent last night about you having one group with only 
one subject?

On 05/06/2015 08:50 AM, Verfaillie, Sander wrote:
>
> Dear Douglasor colleague,
>
> Currently I am working on one of the last steps of freesurfer 
> analyses; the mri_glmdir.
>
> However, trying multiple FSGD versions and after reading several posts 
> one this topic on your Harvard webpage, the "ill-conditioned or badly 
> scaled" message keeps on popping up.
>
> I have checked the number of lines, column spacing. Furthermore I have 
> used excel2.txt conversion for creating the FSGD file, which in 
> previous analyses worked out perfectly fine.
>
> Command line: mri_glmfit --y rh.age_gender_scanner_FU_time.00.mgh
> --fsgd FSGD_v4_2.fsgd dods --C Contrast_test.mtx --surf fsaverage lh 
> --cortex --glmdir rh.FSGD_v4_2_4covariates.glmdir
>
> After visual inspection of the Xg.dat file it seems columns are 
> slightly shifted. I am not sure whether this causes the error.
>
> rh.FSGD_v4_2_4covariates.glmdir/Xg.dat
>
> Could you help me out? I have attached the necessary files.  Sample
> size: n=305, 2 class, 4 covariates
>
> The aim of this analyses is to look at contrast group1>group2 while 
> regressing out the effects of gender, scanner type, age and follow-up 
> time. A second aim is to look at an interaction between FU_time and
> group1>group2.
>
> Thanks a lot in advance, kind regards,
>
> Sander Verfaillie
>
> Drs. S.C.J. Verfaillie
>
> Neuropsycholoog - Onderzoeker
>
> VU Medical Center    Department of Neurology, Alzheimer Center
>
> Department of Radiology & Nuclear Medicine
>
> De Boelelaan 1118, 1081 HZ Amsterdam, the Netherlands
>
> Tel: +31 20 4448527 Room: PK -1 Z 039
>
>
>
> _______________________________________________
> Freesurfer mailing list
> Freesurfer@nmr.mgh.harvard.edu
> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer

--
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
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www.nmr.mgh.harvard.edu/facility/filedrop/index.html
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