Hi Bronwyn,

what Doug indicates here is that he thinks it is possible to do an ANOVA style analysis from a single FSGD and command
(something like this:
https://surfer.nmr.mgh.harvard.edu/fswiki/RepeatedMeasuresAnova )

But this would not be good in situations where you have different many time points per subjects or differently spaced time points. In fact the best way to analyze longitudinal data is to use our Linear Mixed Effects Matlab toolbox. If you have the same number of time points for all subjects and they are spaced approx. the same, the 2-stage model is usually good enough.

See here: https://surfer.nmr.mgh.harvard.edu/fswiki/LongitudinalStatistics for an overview.

Best, Martin


On 09/22/2015 08:53 PM, Bronwyn Overs wrote:
Hi Douglas,

Sorry I don't know what you mean by the different mri_glmfit levels? Also how do you use two fsgd files simultaneously (I assume one file for time 1 and the other for time 2)?

Kind regards,

Bronwyn Overs
Research Assistant

Neuroscience Research Australia

Neuroscience Research Australia
Margarete Ainsworth Building
Barker Street Randwick Sydney NSW 2031 Australia
*M* 0411 308 769 *T* +61 2 9399 1883

neura.edu.au <http://neura.edu.au>

Follow @neuraustralia on twitter <https://twitter.com/neuraustralia>Follow NeuRA on facebook <https://www.facebook.com/NeuroscienceResearchAustralia>Subscribe to the NeuRA Magazine <http://www.neura.edu.au/help-research/subscribe>

On 23/09/2015 12:16 am, Douglas Greve wrote:
If you intend to compute a slope for each subject (first level mri_glmfit), then input the slopes to the 2nd level to test for effects of interest. Is this what you mean? It is probably possible to do this with a single FSGD file and single command line, but it is much easier to set up and understand if you use two.
doug


On 9/22/15 3:13 AM, Bronwyn Overs wrote:
Dear freesurfer mailing list,

Is it possible to run a longitudinal two stage model from the command line using mri_glmift, instead of using the qdec gui? If so, what --y would you pass to use the preprocessed spc values?
--

Kind regards,

Bronwyn Overs
Research Assistant

Neuroscience Research Australia

Neuroscience Research Australia
Margarete Ainsworth Building
Barker Street Randwick Sydney NSW 2031 Australia
*M* 0411 308 769 *T* +61 2 9399 1883

neura.edu.au <http://neura.edu.au>

Follow @neuraustralia on twitter <https://twitter.com/neuraustralia>Follow NeuRA on facebook <https://www.facebook.com/NeuroscienceResearchAustralia>Subscribe to the NeuRA Magazine <http://www.neura.edu.au/help-research/subscribe>



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--
Martin Reuter, PhD
Assistant Professor of Radiology, Harvard Medical School
Assistant Professor of Neurology, Harvard Medical School
A.A.Martinos Center for Biomedical Imaging
Massachusetts General Hospital
Research Affiliate, CSAIL, MIT
Phone: +1-617-724-5652
Web  : http://reuter.mit.edu

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