Hello FSers, quick question on the validity of FS automatic segmentation. I have found longitudinal changes in hippocampus/amygdala volumes. Upon visual inspection, there are some concerning issues, such as the labelling of CSF in the amygdala. Mostly, these amount to a few clusters of between 5-20 voxels around the boundaries of these structures in around 15-20 % of slices. My question is do these errors sounds abnormally high (and don't think so, having seen examples in some lit about FS accuracy), and are these errors acceptable (publishable with a mild degree of confidence) in the context of a longitudinal design, given the high test-retest reliability of FS segmentation? Or are edits necessary? I know there are probably no right/wrong answers on this, but any advice would be greatly appreciated. Best, Garret
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