Thanks Doug. Do I include the TGM as a covariate only for between group comparisons? Do I need to control for it as well if I want to look at the correlation between surface area and age, clinical measures etc. within each group?
Thanks again, Lena From: freesurfer-boun...@nmr.mgh.harvard.edu [mailto:freesurfer-boun...@nmr.mgh.harvard.edu] On Behalf Of Douglas Greve Sent: 28 September 2015 17:18 To: freesurfer@nmr.mgh.harvard.edu Subject: Re: [Freesurfer] total grey matter volume Not for thickness. For surface area it is a good idea to do some kind of normalization. Typically people use the estimated intracranial volume (ICV). You can also use total brain volume or total grey volume. You just need to be aware that each one of these tests something different. On 9/28/15 12:15 PM, Lim, Lena wrote: Dear Experts, Do we need to include total grey matter volume as a covariate in the freesurfer cortical thickness and surface area analyses? I have come across papers that do and don't; so I am not sure if I have to do that. Please kindly advice. Many thanks, Lena _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu<mailto:Freesurfer@nmr.mgh.harvard.edu> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
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