Hi John
yes, they are different methods that measure somewhat different things so
there is no reason they would show the same maps. If you look at volume
change in FS it might be closer, but even that won't match VBM
necessarily
cheers
Bruce
On Fri, 30 Oct 2015, John Anderson wrote:
Hi Doug and Bruce,
Kindly, I have question regarding the difference between voxel based ( VBM/
FSL pipeline) and surface based analysis ( Freesurfer ).
I have two groups of subjects Group A and Group B
I ran morphometric analysis in Freesurfer ( recon-all then manual edits) to
check the difference in cortical thickness between the groups. Then I used
Qdec to correct the results for multiple comparisons and to visualize the
significant clusters.
Then I ran VBM analysis between the groups ( the same subjects) to study the
difference in gray matter volume between the groups.
I got significant difference between the groups in both methods but in
different areas of the brain ( the significant clusters are not in the same
location ).
What is the difference between surface based analysis and voxel based
analysis technically. Is it right to get different results?
Thanks in advance
Bests,
John
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