Hi Martin, thanks for your reply. I have created a qdec file with the fsidtp1.long.fsid.base as first column and specified the long directories with /path_to_data/*.long.*. And each subject has a ?h.thickness file from the recon-process. However, Qdec is asking for a very specific file ?h.thickness.fwhm10.nameoftemplate.mgz or .mgh (even when I pick 0 smoothing).
If I understand correctly, that is the file that I get when running the mris_slope command. But you said I wouldn't need that. Is there a way to get these files for a cross-sectional analysis of the *.long.*.base timepoints? My qdec file currently looks like this: fsid group sex age (in months) ... (behavioral measures) XXXX_1.long.XXXX.base 1 0 52 ... YYYY_1.long.YYYY.base 2 1 48 ... ... Thank you, Clara ----- Ursprüngliche Mail ----- Von: "mreuter" <mreu...@nmr.mgh.harvard.edu> An: freesurfer@nmr.mgh.harvard.edu Gesendet: Dienstag, 8. Dezember 2015 18:14:40 Betreff: Re: [Freesurfer] correlations with longitudinal data Hi Clara, you would do the analysis of a single time point the same way you'd run a regular glm or qdec analysis on cross sectional data. You cannot use LME as that is for longitudinal data (more than 1 time point per subject, at least for most subjects). Also the two stage model, first reduces to multiple measures in each subject to a single measure (slope of the linear fit). It would not be the right tool for selecting a single time point. You could for example create a qdec table with the first row fsid timepoint1.long.base for each subject and then use qdec. If you want to make use of the improved data from the longitudinal image processing, you need to specify the *.long.base directories, so that data is taken from there. Good luck, Martin On 12/08/2015 04:24 AM, Clara Kühn wrote: > Dear FreeSurfer experts, > > I have a subsample of my longitudinal data with 3 scans per subjects fully > preprocessed and would like to start with some simple correlations of > thickness at time 1 with behavioral measures and other factors like age. > > Is there a way to do that with LME (since I was planning on using that as a > method of choice) or is it possible to do that with QDEC? I've prepared my > data for both methods (LME and linear two stage model) but if I use the > cross.qdec.table derived from the longitudinal data, it uses the registered > and smoothed (with mris_slopes) surfaces from the Base, right? > So, I would like to know how I can analyzse a single time point within my > longitudinal design. > > Cheers, > Clara > > -- Martin Reuter, PhD Assistant Professor of Radiology, Harvard Medical School Assistant Professor of Neurology, Harvard Medical School A.A.Martinos Center for Biomedical Imaging Massachusetts General Hospital Research Affiliate, CSAIL, MIT Phone: +1-617-724-5652 Web : http://reuter.mit.edu _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
