btw, what tracer is this? And the asymmetry you are talking about is 
between the hemispheres? Is that typical for this tracer or is this a 
phenomena with this subject (or population)?

On 03/30/2016 03:41 PM, Adam Martersteck wrote:
> Hi Freesurfer team,
>
> I’m encountering a problem using bbregister on PET data:
>
> -- When I attempt to register a PET volume to T1-space the asymmetric 
> tracer uptake of the PET throws off proper registration. (Treating the 
> PET as a T1 because of the non-specific white matter uptake > grey 
> matter signal).
>
> -- You can really see the bbregister mis-registration in this gif 
> here: https://goo.gl/iM6yrT
>
> -- It (expectedly) attempts to find the best match between signal 
> intensities on both the left and right surfaces, but is inherently 
> biased by the asymmetric uptake shifts the entire volume to the right.
>
> -- Are there any suggestions for dealing with asymmetric scans like 
> this? Stick with just a simple FLIRT? It doesn't seem to do that great 
> a job for everyone.
>
> Cutting left and right hemispheres apart and register separately?
>
> Using Martin’s new robust register for multi-modal data? Any 
> suggestions on the parameters of ROBENT?
>
> Thanks,
> Adam
>
>
> _______________________________________________
> Freesurfer mailing list
> Freesurfer@nmr.mgh.harvard.edu
> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer

-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
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