Hi William,

either way is fine, as long as you don't mix results from cross and long 
processing in your analysis. Since all images need to go through the 
cross sectional stream anyway, I think actually (2) will be less 
processing (and potentially less QC and editing).

Best, Martin


On 06/10/2016 09:12 AM, William Baare wrote:
> Hi
>
> I have two groups I want to compare, in total 172 scans
> Of these 78 got a a follow up. Groups are approximately evenly distributed.
>
> I want to do first a cross sectional comparison and subsequently a 
> longitudinal analysis for the 78 subjects only.
>
> My question is:
> (1) Is it is valid to analyse all data using the longitudinal processing 
> stream ( e.g. recon-all -all, recon-all -base, recon-all -long), even though 
> I do separate  cross sectional and longitudinal analyses? Or (2) should I 
> analyse first the 175 using the cross sectional stream and then separately 
> analyse the 78 with a follow up scan with the longitudinal stream?
>
>
> Of course I would prefer option 1 as that would reduce potential 
> editing/adjusting
>
> many thanks in advance
> William
>
>
>
>
>   
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>

-- 
Martin Reuter, PhD
Assistant Professor of Radiology, Harvard Medical School
Assistant Professor of Neurology, Harvard Medical School
A.A.Martinos Center for Biomedical Imaging
Massachusetts General Hospital
Research Affiliate, CSAIL, MIT
Phone: +1-617-724-5652
Web  : http://reuter.mit.edu

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