> Date: Thu, 14 Jul 2016 10:35:43 -0400 (EDT)
> From: Lilla Zollei <lzol...@nmr.mgh.harvard.edu>
> Subject: Re: [Freesurfer] CVS question
> To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
> Message-ID:
>       <alpine.lrh.2.20.1607121530370.50...@semmelweis.nmr.mgh.harvard.edu>
> Content-Type: text/plain; charset="utf-8"
> 
> 
> Hi Michael,
> 
>> I want to compare two populations using CVS so I can cross-register 
>> multimodal maps (e.g. ASL, FA, QSM) for volumetric comparisons.
>> 
>> I?ve gotten CVS to work very well registering one subject to another, it 
>> really is impressive
>> 
>> However, using the --mni option, it doesn?t work so well, perhaps because 
>> the atlas is so averaged together and smoothed out, the images look highly 
>> warped.
>> 
>> I know I can pick a subject at random, and register everything to that, but 
>> that may induce some biases. The following website suggests I might try 
>> simply creating my own atlas (under the answers to Nov 2014 course 
>> questions):?https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/QuestionAnswers
>> 
>> Seems like they register 40 subjects with each other for multiple 
>> iterations, average the brain together, then run recon-all on that. How does 
>> one actually do that, however? i.e. 1st round, register everyone to subject 
>> 1 ? then what? Seems like somehow you would want a registration intermediate 
>> point somehow?
> 
> Have you tried to use the default cvs atlas? If you do not indicate any 
> explicit targets that is what will get used. I think that might be a 
> solution that you are looking for.
> 
> Lilla
> 
> ------------------------------
> 

Thank you, I happened to try that after I had sent this help request, and yes, 
it works much, much better. The transformation to MNI space is highly warped, 
that I realize was the problem. Thank you for your help.




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