I would still say no -- the differences could still be due to 
differences in acquisition parameters


On 10/03/2016 02:30 PM, Martin Juneja wrote:
> Thanks Dr. Harms and Dr. Greve.
> So can I do the cortical thickness comparison if we have healthy 
> controls data from the same scanner but acquired using different 
> protocol e.g. if we get access of age-matched healthy controls data 
> from another lab who used the same scanner?
>
> Thanks.
>
> On Fri, Sep 30, 2016 at 12:02 PM, Douglas N Greve 
> <gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>> wrote:
>
>     You can do the comparison, but the interpretation is difficult. If you
>     see a difference, how do you know it is not due to the scanner?
>     There's
>     not much you can do ...
>
>
>     On 09/29/2016 02:54 PM, Martin Juneja wrote:
>     > Hello FS experts,
>     >
>     > I have a data set of 20 subjects (patients) collected at location-1
>     > with 3T Siemens scanner. Also, I have a set of age-matched 20
>     subjects
>     > (controls) collected at location-2 with 3T Siemens scanner.
>     >
>     > I am interested in comparing cortical thickness between controls and
>     > patients using FreeSurfer but I am not sure if I can do that since I
>     > have both the data sets collected at two different locations.
>     >
>     > I would really appreciate any inputs on this.
>     >
>     > I tried to find some papers on scanner differences but all I could
>     > find was between 1.5 T vs 3T or 3T vs 7T. Is there any special
>     > covariates I need to define for this purpose (if so then at
>     which step
>     > during analysis?) or is it not possible at all?
>     >
>     > Thanks.
>     >
>     >
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>     --
>     Douglas N. Greve, Ph.D.
>     MGH-NMR Center
>     gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>
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-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
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www.nmr.mgh.harvard.edu/facility/filedrop/index.html
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