I don't think we have anything yet that will do this for the thalamus. If you have highres data that is full brain T1 you can analyze it in its native space in the upcoming 6.0 On Mon, 24 Oct 2016, Dorsa Haji Ghaffari wrote:



So what I understand is that we can do the segmentation using the whole
brain MRI and then use the higher contrast MRI to refine the thalamus
segmentation? if so, can you explain more about it?
Thank you

Dorsa

On Thu, Oct 20, 2016 at 12:20 PM, Bruce Fischl <fis...@nmr.mgh.harvard.edu>
wrote:
      no, you need full brain coverage in at least one, but we do have
      some prototype tools that use a smaller FOV image after a recon
      to segment specific structures (including at least a bit of work
      on the STN).

      As I said though, depending on the details of the 40 slice image
      I would be cautious about using it as a gold-standard to
      interpret the T1. I would need more information to say for sure


      On Thu, 20 Oct 2016, Dorsa Haji Ghaffari wrote:

            So basically we have two types of images. One has a
            better contrast for seeing the STN to that we can
            target it for deep brain
            stimulation, but that one is only 40 slices and is
            not the whole brain. We have another set of images
            which is complete but does
            not have a good contrast for showing the
            sub-cortical structures. I have attached a sample of
            each one. I have also attached my
            subject. Does Freesurfer work with only 40 slices?

            On Thu, Oct 20, 2016 at 9:51 AM, Bruce Fischl
            <fis...@nmr.mgh.harvard.edu> wrote:
                  Hi Dorsa

                  if you upload your subject I'll take a look.
            What is a 3TC image? I don't know what contrast the
            image you sent is
                  but I would be cautious about only using it to
            assess the accuracy of the T1 segmentation

                  cheers
                  Bruce

                  On Wed, 19 Oct 2016, Dorsa Haji Ghaffari
            wrote:

                        I have attached a screenshot of one of
            the slices. from what I see it is going a little far
            in the
                        medial and lateral parts. I am using a
            3TC image taken by Philips device. Is there any way
            to limit the
                        region of interest before running the
            recon-all to only segment the thalamus and may give
            better
                        results?
                        Thank you

                        Dorsa

                        On Wed, Oct 19, 2016 at 5:21 PM, Bruce
            Fischl <fis...@nmr.mgh.harvard.edu> wrote:
                              Hi Dorsa

                              why do you think it  is going out
            too far? What intensity volume are you
                              overlaying it on? Many
            segmentations miss the lateral parts of the
                              thalamus since they have so much
            myelin in them

                              cheers
                              Bruce
                              On Wed, 19 Oct 2016, Dorsa
                              Haji Ghaffari wrote:

                              > Hi,
                              > I have done the sub-cortical
            segmentation in Freesurfer and have extracted the
            left
                              thalamus, when I put
                              > it on top of the original MRI,
            it seems like it is getting out of the border of
            thalamus,
                              also it is not
                              > smooth. I wanted to ask if
            anyone knows how to limit the computation only to
            thalamus, and
                              also make it
                              > trace the thalamus more
            accurately?
                              >
                              > Thank you
                              >
                              > Dorsa
                              >
                              >
                       
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            On Thu, Oct 20, 2016 at 9:51 AM, Bruce Fischl
            <fis...@nmr.mgh.harvard.edu> wrote:
                  Hi Dorsa

                  if you upload your subject I'll take a look.
            What is a 3TC image? I don't know what contrast the
            image you sent is
                  but I would be cautious about only using it to
            assess the accuracy of the T1 segmentation

                  cheers
                  Bruce

                  On Wed, 19 Oct 2016, Dorsa Haji Ghaffari
            wrote:

                        I have attached a screenshot of one of
            the slices. from what I see it is going a little far
            in the
                        medial and lateral parts. I am using a
            3TC image taken by Philips device. Is there any way
            to limit the
                        region of interest before running the
            recon-all to only segment the thalamus and may give
            better
                        results?
                        Thank you

                        Dorsa

                        On Wed, Oct 19, 2016 at 5:21 PM, Bruce
            Fischl <fis...@nmr.mgh.harvard.edu> wrote:
                              Hi Dorsa

                              why do you think it  is going out
            too far? What intensity volume are you
                              overlaying it on? Many
            segmentations miss the lateral parts of the
                              thalamus since they have so much
            myelin in them

                              cheers
                              Bruce
                              On Wed, 19 Oct 2016, Dorsa
                              Haji Ghaffari wrote:

                              > Hi,
                              > I have done the sub-cortical
            segmentation in Freesurfer and have extracted the
            left
                              thalamus, when I put
                              > it on top of the original MRI,
            it seems like it is getting out of the border of
            thalamus,
                              also it is not
                              > smooth. I wanted to ask if
            anyone knows how to limit the computation only to
            thalamus, and
                              also make it
                              > trace the thalamus more
            accurately?
                              >
                              > Thank you
                              >
                              > Dorsa
                              >
                              >
                       
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