I would say yes, but I've seen plenty of pubs that do not correct. The bonferroni correction is fine. You could also try FDR (though on 4 points it might not make much sense).
On 01/10/2017 01:47 PM, neuroimage analyst wrote: > Hi, > > I extracted thalamic, caudate, and putamen volume (left hemisphere), > and cingulate thickness (right hemisphere) from > freesurfer's parcellation. Then I compare these volumes and thickness > across two groups using R and found significant differences in these > measurements. Do I have to correct for multiple comparisons? > > If yes, how do I do that? Does this make sense to divide the p-value/4 > and if the p-value < p-value/4 then the test is Bonferroni corrected? > If no, what do I say in my results that the test statistic is not > inflated? > > Thanks > > Regards > > --VM > > > _______________________________________________ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer -- Douglas N. Greve, Ph.D. MGH-NMR Center gr...@nmr.mgh.harvard.edu Phone Number: 617-724-2358 Fax: 617-726-7422 Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2 www.nmr.mgh.harvard.edu/facility/filedrop/index.html Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/ _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.
