Dear Freesurfer experts,
I would like to set up a design matrix for a design that is not
QDEC-able. I have three categorical factors:
1.disease status: 2 levels
2.gender: 2 levels
3.scan site: 4 levels
The first design I set up was the following (the rows are just for
illustration and don’t reflect the number of subjects that will enter
the analysis):
designs4_fs_mailinglist.png
However, I have my doubts as to the “efficiency” of the design (in terms
of number of regressors / DOF). Therefore, here is my second design:
Would this design be correct for assessing the group differences for
disease status while regressing out gender and scanner site? My
understanding is, that in this design I can’t assess the effects of
interactions regarding scanner site. However, I think it is fair to
assume that the scanner site doesn’t have a differential effect on
either gender or disease status. Any feedback is highly appreciated.
Thanks a lot. Best regards,
Tim
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