Hi Antonin,

Thanks a lot for your reply.

Somehow, in the link you sent, I could not find any response to your email.
But I can see your email to Anderson and command line parameters.

As I am not an expert in using FreeSurfer, so would it be possible for you
to share detailed step-by-step guide and PALM command after I run mri_glmfit
command and how and where to include '?h.white.avg.area.mgh' file?

I would really appreciate any help.

On Mon, Mar 6, 2017 at 4:28 PM, Antonin Skoch <a...@ikem.cz> wrote:

> Dear Martin,
>
> I think yes, you can use PALM with FreeSurfer surfaces, see my
> conversation with Anderson on FSL list:
>
> https://www.jiscmail.ac.uk/cgi-bin/webadmin?A2=ind1604&L=
> FSL&D=0&1=FSL&9=A&J=on&d=No+Match%3BMatch%3BMatches&z=4&P=239088
>
> but beware not to forget to include average the vertex area
> (?h.white.avg.area.mgh) file.
>
> Antonin
>
>
> If you don't have an orthogonal design, then you can't use
> mri_glmfit-sim. I think you can use PALM:
>
> https://fsl.fmrib.ox.ac.uk/fsl/fslwiki/PALM
>
> I have not tried it yet.
>
> Anderson, can you use PALM with surfaces?
>
>
>
>
>
>
> On 03/06/2017 05:23 PM, Martin Juneja wrote:
> > Hi Dr. Greve,
> >
> > I tried to run: mri_glmfit-sim --glmdir lh.MEQ_LGI.glmdir --sim perm
> > 1000 3 permcsd --sim-sign abs --cwpvalthresh .05
> > It gives error that ERROR: design matrix is not orthogonal, cannot be
> > used with permutation.
> >
> > But when I run: mri_glmfit-sim --glmdir lh.MEQ_LGI.glmdir --sim perm
> > 1000 3 permcsd --sim-sign abs --cwpvalthresh .05 --perm-force, it works.
> >
> > I am not sure whether I will have to make the design matrix
> > orthogonal. If so, could you please tell me how that can be done?
> >
> > Or using --perm-force should be fine?
> >
> > Thanks.
> >
> > On Mon, Mar 6, 2017 at 1:58 PM, Douglas N Greve
> > <gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu 
> > <gr...@nmr.mgh.harvard.edu>>> wrote:
> >
> >     This is a problem with using LGI in that it is already extremely
> >     smooth
> >     that the smoothness exceeds the limit of the look up table that we
> >     supply. I  recommend that you not use a gaussian-based correction for
> >     LGI. Instead, use permutation (see mri_glmfit-sim --help).
> >
> >
> >
> >     On 03/06/2017 01:36 PM, Martin Juneja wrote:
> >     > Hello everyone,
> >     >
> >     > I am trying to extract clusters showing significant correlation
> >     > between LGI and a behavioral measure. I am able to extract PCC and
> >     > sig.mgh but at the last step when I try to run simulation command to
> >     > view corrected results and I run:
> >     >
> >     > mri_glmfit-sim --glmdir lh.MEQ_LGI.glmdir --cache 4 neg --cwp 0.05
> >     > --2spaces
> >     >
> >     > I get following error:
> >     >
> >     > ERROR: cannot find
> >     >
> >
> > /usr/local/freesurfer/average/mult-comp-cor/fsaverage/lh/cortex/fwhm35/neg/th40/mc-z.csd
> >     >
> >     > But I can see mc-z.csd file in fwhm30 etc.
> >     >
> >     > Full message on terminal window is attached following.
> >     >
> >     > Any help would be really appreciated.
> >     >
> >     > ----- Full message ----
> >     >
> >     > cmdline mri_glmfit.bin --y lh.MEQ_LGI.10.mgh --fsgd MEQ.fsgd
> >     dods --C
> >     > Corr-MEQ-cor.mtx --surf fsaverage lh --cortex --glmdir
> >     lh.MEQ_LGI.glmdir
> >     >
> >     > WARNING: unrecognized mri_glmfit cmd option mri_glmfit.bin
> >     >
> >     > SURFACE: fsaverage lh
> >     >
> >     > log file is lh.MEQ_LGI.glmdir/cache.mri_glmfit-sim.log
> >     >
> >     > /usr/local/freesurfer/bin/mri_glmfit-sim
> >     >
> >     > --glmdir lh.MEQ_LGI.glmdir --cache 4 neg --cwp 0.05 --2spaces
> >     >
> >     > $Id: mri_glmfit-sim,v 1.60 2016/04/30 15:13:36 greve Exp $
> >     >
> >     > Mon Mar  6 11:11:13 MST 2017
> >     >
> >     > setenv SUBJECTS_DIR
> >     > /data/emot/Freesurfer/FreeSurferSegmentation/SB_AgingAll
> >     >
> >     > FREESURFER_HOME /usr/local/freesurfer
> >     >
> >     > Original mri_glmfit command line:
> >     >
> >     > cmdline mri_glmfit.bin --y lh.MEQ_LGI.10.mgh --fsgd MEQ.fsgd
> >     dods --C
> >     > Corr-MEQ-cor.mtx --surf fsaverage lh --cortex --glmdir
> >     lh.MEQ_LGI.glmdir
> >     >
> >     > DoSim = 0
> >     >
> >     > UseCache = 1
> >     >
> >     > DoPoll = 0
> >     >
> >     > DoPBSubmit = 0
> >     >
> >     > DoBackground = 0
> >     >
> >     > DiagCluster = 0
> >     >
> >     > gd2mtx = dods
> >     >
> >     > fwhm = 35.073391
> >     >
> >     > ERROR: cannot find
> >     >
> >
> > /usr/local/freesurfer/average/mult-comp-cor/fsaverage/lh/cortex/fwhm35/neg/th40/mc-z.csd
> >     >
> >     >
>
>
>
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