no, that is fine too

On 03/15/2017 04:49 PM, Mihaela Stefan wrote:
> I was thinking to use lme_mass_FDR2 to correct for multiple 
> comparisons. Is there a reason not to use it in this case?
>
> Thank you!
> Mihaela
>
> On Wed, Mar 15, 2017 at 3:55 PM, Douglas N Greve 
> <gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>> wrote:
>
>     No, there is not. You can do it that way if you want to. The
>     problem is
>     that you then end up with stuff outside of the ROI smoothing into the
>     ROI. Also note that either way, you will need to generate new
>     tables for
>     correction of multiple comparisons (use use permutation)
>
>
>     On 03/15/2017 03:52 PM, Mihaela Stefan wrote:
>     > Is there a way or reference this smoothing detail in a paper? There
>     > are people who believe that the soothing should be done at the whole
>     > brain level and then apply the mask (--label), during the GLM
>     analysis.
>     >
>     > Thanks again!
>     > Mihaela
>     >
>     > On Wed, Mar 15, 2017 at 3:12 PM, Douglas N Greve
>     > <gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>
>     <mailto:gr...@nmr.mgh.harvard.edu
>     <mailto:gr...@nmr.mgh.harvard.edu>>> wrote:
>     >
>     >     yes, that is the right way to do it
>     >
>     >
>     >     On 03/15/2017 01:18 PM, Mihaela Stefan wrote:
>     >     > Hello FreeSurfers,
>     >     >
>     >     > I would like to run a group analysis on cortical thickness
>     using
>     >     > existing Desikan labels.
>     >     >
>     >     > When I run the command for smoothing, should I replace
>     >     *--cortex* with
>     >     > *--label-trg*? In other words, for ROI analysis, should we
>     smooth
>     >     > *only* the target mask?
>     >     >
>     >     > mri_surf2surf --hemi lh \
>     >     >    --s fsaverage \
>     >     >    --sval lh.gender_age.thickness.00.mgh \
>     >     >    --fwhm 10 \
>     >     >   *--cortex*  \
>     >     >    --tval lh.gender_age.thickness.10B.mgh
>     >     >
>     >     >
>     >     > I followed the instructions from here:
>     >     >
>     >
>     https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/GroupAnalysis
>     <https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/GroupAnalysis>
>     >   
>      <https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/GroupAnalysis
>     <https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/GroupAnalysis>>
>     >     >
>     >
>     https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/AnatomicalROI
>     <https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/AnatomicalROI>
>     >   
>      <https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/AnatomicalROI
>     <https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/AnatomicalROI>>
>     >     > https://surfer.nmr.mgh.harvard.edu/fswiki/mri_glmfit
>     <https://surfer.nmr.mgh.harvard.edu/fswiki/mri_glmfit>
>     >     <https://surfer.nmr.mgh.harvard.edu/fswiki/mri_glmfit
>     <https://surfer.nmr.mgh.harvard.edu/fswiki/mri_glmfit>>
>     >     > http://freesurfer.net/fswiki/mri_surf2surf
>     <http://freesurfer.net/fswiki/mri_surf2surf>
>     >     <http://freesurfer.net/fswiki/mri_surf2surf
>     <http://freesurfer.net/fswiki/mri_surf2surf>>
>     >     > Thank you!
>     >     > Mihaela
>     >     >
>     >     >
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>     >
>     >     --
>     >     Douglas N. Greve, Ph.D.
>     >     MGH-NMR Center
>     > gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>
>     <mailto:gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>>
>     >     Phone Number: 617-724-2358 <tel:617-724-2358>
>     <tel:617-724-2358 <tel:617-724-2358>>
>     >     Fax: 617-726-7422 <tel:617-726-7422> <tel:617-726-7422
>     <tel:617-726-7422>>
>     >
>     >     Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
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>     <http://surfer.nmr.mgh.harvard.edu/fswiki/BugReporting>>
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>     >     <https://gate.nmr.mgh.harvard.edu/filedrop2
>     <https://gate.nmr.mgh.harvard.edu/filedrop2>>
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>     >
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>     --
>     Douglas N. Greve, Ph.D.
>     MGH-NMR Center
>     gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>
>     Phone Number: 617-724-2358 <tel:617-724-2358>
>     Fax: 617-726-7422 <tel:617-726-7422>
>
>     Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
>     <http://surfer.nmr.mgh.harvard.edu/fswiki/BugReporting>
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>     <https://gate.nmr.mgh.harvard.edu/filedrop2>
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-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
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www.nmr.mgh.harvard.edu/facility/filedrop/index.html
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