Hi Batool - Yes, it would be a problem. It'd be similar to having some scans 
with one spatial resolution and some with another, or administering one 
questionnaire to some of your subjects and a different one to the others and 
then trying to compare the answers. If the 16 directions are a subset of the 49 
directions, then you can discard the remaining 33 directions from the subjects 
that have 49.

Best,
a.y

________________________________
From: freesurfer-boun...@nmr.mgh.harvard.edu 
[freesurfer-boun...@nmr.mgh.harvard.edu] on behalf of Rizvi, Batool 
[br2...@cumc.columbia.edu]
Sent: Wednesday, March 29, 2017 8:37 AM
To: freesurfer@nmr.mgh.harvard.edu
Subject: [Freesurfer] TRACULA - subjects with different number of directions

Hi,

We were wondering if it would be an issue if we used a dataset in which we 
included 5 subjects that have a different number of directions (49 directions) 
than the rest of the subjects with a standard number (16 directions). Even if 
the preprocessing steps work, will it be an issue comparing the subjects 
statistically?

If so, how can we treat the 5 subjects differently, but still include them in 
our study?

Thank you!
Batool
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