I have a group of subjects, scans at time1 and time2 that have been run through 
the longitudinal stream.  I have a group of ROIs in MNI space that I've been 
able to push up to fsaverage following the VolumeRoiCorticalThickness tutorial:

https://surfer.nmr.mgh.harvard.edu/fswiki/VolumeRoiCorticalThickness

Further, I've used mri_surf2surf to push the mgh file to each subject.

I'm using mri_segstats to pull out mean thickness and a few other variables.  
If I load the mgh into tksurfer and create a label by hand (~99% the same), I 
can use mris_anatomical_stats which will also output surface area.  I can also 
use the label with mri_segstats (--slabel) to calculate the thickness, etc. and 
those values match the ones from mris_anatomical_stats.

Based on the input (mgh or label), I get either voxels or vertices.  While not 
exactly the same and possibly due to creating the label by hand, the numbers 
are very close.  However, the volume reported (GrayVol for 
mris_anatomical_stats, Volume_mm3 for mri_segstats) are really different 
between the two methods.  In checking a few subjects, the volume reported for 
mris_anatomical_stats is usually 2-3 times larger than mri_segstats.  Why is 
this?  Which volume is correct?  Is there a way to make one program calculate a 
volume more in line with the other?  Less important, is there a way to force 
mri_segstats to output surface area?

Thank you for taking the time to read this

-Joel


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