Okay, understood. Thanks again for your help.

Best regards,
Jake


On Fri, Jul 28, 2017 at 11:20 AM, Bruce Fischl <fis...@nmr.mgh.harvard.edu>
wrote:

> it depends. In this case you want to erase as it creates an incorrect
> connection. In others you want to add if there is an incorrect break
> On Fri, 28 Jul 2017, Jake Rieke wrote:
>
> Thanks, Bruce and Douglas! Looking at the surface prior to the topology
>> correction step has been very helpful. I can see the region you pointed
>> out
>> - where the wm.mgz connects to the body of the wm, disconnects, and then
>> reconnects at a different spot. I'm having some trouble implementing the
>> manual edits to the wm.mgz.
>> Part of the problem is that I'm still training my eye to differentiate GM
>> and WM (especially in cases with thin tracts or partial voluming), but
>> this
>> gives me a great place to start.
>>
>> I'm wondering, in general, is the idea to erase or add voxels in the
>> wm.mgz
>> where the defects are located? In other words, defects can be interpreted
>> as
>> areas of misclassified as WM? In this case, it seems that I need to focus
>> on
>> deleting voxels in the wm.mgz that are incorrectly segmented.
>>
>> Thanks,
>> Jake
>>
>> Biomedical Engineer, Brain Rehabilitation Research CenterMalcolm Randall
>> VA
>> Medical Center, 1601 SW Archer Road, Gainesville, FL 32608
>> Phone: 1-352-376-1611 ext. 5249, E-mail: jakeri...@gmail.com
>>
>> On Thu, Jul 27, 2017 at 1:09 PM, Bruce Fischl <fis...@nmr.mgh.harvard.edu
>> >
>> wrote:
>>       Hi Jake
>>
>>       there are voxels like 173, 112, 122 that are incorrectly
>>       segmented as wm (that is, they have a value >=5 in the wm.mgz)
>>       that connect two adjenct gyri. You can either change the
>>       intensity thresholds in mri_segment, or manually erase some of
>>       them. The best way to see this is to look at the surface prior
>>       to topology correction, and color it with defect numbers so you
>>       can see where the defects are. Something like:
>>
>>       cd $SUBJECTS_DIR/<subject id>/mri
>>       freeview -v brain.mgz wm.mgz:colormap=heat:heatscale=1,100 \
>>               -f../surf/lh.orig.nofix:overlay=../surf/lh.defect_labels:
>> overlay_threshold=1,
>>       255:edgecolor=overlay \
>>               -slice 172 123 134
>>
>>
>>       if you page through a few axial slices you will see that the
>>       wm.mgz is connected to the body of the wm in slice 109,
>>       disconnecs in 110, then reconnects to a different part in 115,
>>       which should never happen
>>
>>       cheers
>>       Bruce
>>        On Thu, 27 Jul 2017, Jake Rieke wrote:
>>
>>             Hi Bruce,
>>
>>             Thanks for the response. I just uploaded the subject
>>             using the ftp file
>>             exchange. The issue is visible in the region close
>>             to voxel coordinate [172,
>>             123 ,134]. the missing gyrus is capped between
>>             coronal slice 141 to 118. I
>>             forgot to mention in my first message that we used a
>>             T2 to improve pial
>>             surface after initial running with just the T1.
>>
>>             Thanks again
>>             Jake
>>
>>             Biomedical Engineer, Brain Rehabilitation Research
>>             CenterMalcolm Randall VA
>>             Medical Center, 1601 SW Archer Road, Gainesville, FL
>>             32608
>>             Phone: 1-352-376-1611 ext. 5249, E-mail:
>>             jakeri...@gmail.com
>>
>>             On Wed, Jul 26, 2017 at 8:16 PM, Bruce Fischl
>>             <fis...@nmr.mgh.harvard.edu>
>>             wrote:
>>                   Hi Jake
>>
>>                   usually that means that there is a topology
>>             defect that is being
>>                   incorrectly fixed. If you upload the subject
>>             and point us at the
>>                   voxel
>>                   coords we will take a look
>>
>>                   cheers
>>                   Bruce
>>
>>                   On Wed, 26 Jul 2017, Jake Rieke wrote:
>>
>>                   > Hello surfers,
>>                   >
>>                   > I'm attempting to extend white and pial
>>             surfaces to encompass
>>                   an
>>                   > unrecognized gyrus. The wm.mgz seems include
>>             the WM tissue,
>>                   but the white
>>                   > surface does not extend to the WM boundary.
>>             I thought this
>>                   might be related
>>                   > to an intensity normalization error and
>>             tried using control
>>                   points, but that
>>                   > did not make a big difference in the
>>             resulting surfaces. I've
>>                   attached
>>                   > pictures to better illustrate the problem.
>>             Thanks in advance
>>                   for your help!
>>                   >
>>                   > Best regards,
>>                   > Jake
>>                   >
>>                   >
>>                   >
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