Thank you for your reply!

Ilona
________________________________________
Lähettäjä: freesurfer-boun...@nmr.mgh.harvard.edu 
[freesurfer-boun...@nmr.mgh.harvard.edu] käyttäjän Bruce Fischl 
[fis...@nmr.mgh.harvard.edu] puolesta
Lähetetty: 6. syyskuuta 2017 16:56
Vastaanottaja: Freesurfer support list
Aihe: Re: [Freesurfer] wm topological defects

Hi Ilona

yes, you only need to edit the wm in regions where inaccuracies in the
wm.mgz are making the surfaces inaccurate
cheers
Bruce



On
Wed, 6 Sep 2017, Ruotsalainen, Ilona wrote:

> Dear experts,
>
> I would have a follow up question for this thread.
>
> I have erased voxels from areas which are not white matter, but classified as 
> white matter in wm.mgz (such as blood vessels and tissue outside brain that 
> clearly are not white matter) or filled "holes" in wm.mgz (example in 
> pictures hole_wm1 and hole_wm2). I have done this even the surfaces look 
> accurate.  After checking the aparc.stats-file there are sometimes quite 
> large changes in volumes of specific areas (even over 10%). So my question is 
> following. Should I only fix those parts in wm.mgz in which the ?h.pial 
> and/or ?h.white are not accurate and leave other parts of wm.mgz unfixed even 
> the mask clearly includes regions that are not white matter? I have read the 
> tutorials, but I'm still not certain about this issue.
>
> Thank you,
> Ilona Ruotsalainen
>
>
>
>
> -----Original Message-----
> From: freesurfer-boun...@nmr.mgh.harvard.edu 
> [mailto:freesurfer-boun...@nmr.mgh.harvard.edu] On Behalf Of Bruce Fischl
> Sent: tiistai 4. heinäkuuta 2017 20:43
> To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
> Subject: Re: [Freesurfer] wm topological defects
>
> Hi Manuel
>
> you should examine the ?h.white and ?h.pial for accuracy, and only use the 
> .nofix surfaces if you are trying to figure out why the white/pial are not as 
> accurate as you would like Bruce
>
>
> On Tue, 4 Jul 2017, Manuel Delgado wrote:
>
>> Dear all:
>> Regarding wm edits, it is shown in the tutorial how to proceed with "holes"
>> that appear in the smoothwm.nofix. However, those holes do not
>> necessarily affect the wm matter surface. So is it recommendable to
>> check if holes in the smoothwm.nofix surface affect the real wm
>> surface before correcting them? And, what is the purpose of the
>> smoothwm.nofix, is it used for other issues?
>> Thank you
>>
>> --
>> Manuel Delgado Alvarado, MD
>>
>> Predoctoral Researcher
>> Neuroimaging Unit, IDIVAL
>> [LogoIDIVAL.PNG?ver=2015-10-14-180234-000]
>> Avda. Cardenal Herrera Oria s/n
>> 39011 Santander, Spain
>>
>>
>>
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